Protein Information

Name tumor necrosis factor alpha
Synonyms Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2…

Compound Information

Name propanil
CAS

Reference List

PubMed Abstract RScore(About this table)
11312646 Frost LL, Neeley YX, Schafer R, Gibson LF, Barnett JB: Propanil inhibits tumor necrosis factor-alpha production by reducing nuclear levels of the transcription factor nuclear factor-kappab in the macrophage cell line ic-21. Toxicol Appl Pharmacol. 2001 May 1;172(3):186-93.
82(1,1,1,2) Details
9201266 Xie YC, Schafer R, Barnett JB: Inhibitory effect of 3,4-dichloro-propionaniline on cytokine production by macrophages is associated with LPS-mediated signal transduction. J Leukoc Biol. 1997 Jun;61(6):745-52.

Our previous studies demonstrated that both in vivo and in vitro 3,4-dichloro-propionanilide (propanil) exposure inhibited interleukin-6 (IL-6) and tumor necrosis factor (TNF) production by adherent thioglycollate-elicited peritoneal cells (macrophages) after lipopolysaccharide (LPS) stimulation.
81(1,1,1,1) Details
9221836 Xie YC, Schafer R, Barnett JB: The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production. Toxicol Appl Pharmacol. 1997 Jul;145(1):184-91.
32(0,1,1,2) Details
7679225 Theus SA, Tabor DR, Gandy J, Barnett JB: Alteration of macrophage cytotoxicity through endogenous interferon and tumor necrosis factor alpha induction by propanil. Toxicol Appl Pharmacol. 1993 Jan;118(1):46-52.
12(0,0,2,2) Details