Protein Information

Name hemoglobin (protein family or complex)
Synonyms Hemoglobin; Hemoglobins

Compound Information

Name propanil
CAS

Reference List

PubMed Abstract RScore(About this table)
2237922 McMillan DC, McRae TA, Hinson JA: Propanil-induced methemoglobinemia and hemoglobin binding in the rat. Toxicol Appl Pharmacol. 1990 Sep 15;105(3):503-7.

These data suggest that human exposure to propanil may be monitored in the absence of observable toxicity by the analysis of propanil metabolites bound to hemoglobin.
122(1,2,3,7) Details
2315934 McMillan DC, Freeman JP, Hinson JA: Metabolism of the arylamide herbicide propanil. Toxicol Appl Pharmacol. 1990 Mar 15;103(1):90-101.

Both N-hydroxy-3,4-dichloroaniline and 6-hydroxy-3,4-dichloroaniline directly oxidized hemoglobin in rat erythrocyte suspensions in a concentration-dependent manner; however, the potency of N-hydroxy-3,4-dichloroaniline was at least an order of magnitude greater than that of 6-hydroxy-3,4-dichloroaniline.
1(0,0,0,1) Details
12748691 : NTP Toxicology and Carcinogenesis Studies of 1,2-Dichlorobenzene (o-Dichlorobenzene) (CAS No. 95-50-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Natl Toxicol Program Tech Rep Ser. 1985 Oct;255:1-195.


The major use of 1,2-dichlorobenzene is as an intermediate in the synthesis of several organic compounds (e.g. 3,4-dichloroaniline) and in the syntheses of the herbicides propanil, diuron, and neburon.
0(0,0,0,0) Details