| Name | interleukin 6 |
|---|---|
| Synonyms | 26 kd protein; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; HGF… |
| Name | propanil |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9221836 | Xie YC, Schafer R, Barnett JB: The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production. Toxicol Appl Pharmacol. 1997 Jul;145(1):184-91. Both oral and i.p. propanil exposure resulted in up to a 60-70% reduction in IL-6 and TNF-alpha production by the LPS-stimulated macrophages, depending on the route, postexposure time, and dose of propanil administered. |
114(1,2,2,4) | Details |
| 9761131 | Zhao W, Schafer R, Barnett JB: Cytokine production by C57BL/6 mouse spleen cells is selectively reduced by exposure to propanil. J Toxicol Environ Health A. 1998 Sep 25;55(2):107-20. In vivo exposure to propanil caused the reduction of interleukin (IL)-2, IL-6, granulocyte-macrophage colony-stimulating factor (GM-CSF), and interferon (IFN)-gamma production in concanavalin A-stimulated spleen cell cultures established 2 d after exposure. |
113(1,2,2,3) | Details |
| 9201266 | Xie YC, Schafer R, Barnett JB: Inhibitory effect of 3,4-dichloro-propionaniline on cytokine production by macrophages is associated with LPS-mediated signal transduction. J Leukoc Biol. 1997 Jun;61(6):745-52. Our previous studies demonstrated that both in vivo and in vitro 3,4-dichloro-propionanilide (propanil) exposure inhibited interleukin-6 (IL-6) and tumor necrosis factor (TNF) production by adherent thioglycollate-elicited peritoneal cells (macrophages) after lipopolysaccharide (LPS) stimulation. |
81(1,1,1,1) | Details |
| 17585980 | Corsini E, Codeca I, Mangiaratti S, Birindelli S, Minoia C, Turci R, Viviani B, Facchi A, Vitelli N, Lucchi L, Galli CL, Marinovich M, Colosio C: Immunomodulatory effects of the herbicide propanil on cytokine production in humans: In vivo and in vitro exposure. Toxicol Appl Pharmacol. 2007 Jul 15;222(2):202-10. Epub 2007 May 21. The investigation of serum, cellular, and functional immune parameters suggested that propanil exposure results in a modest immunomodulatory effect, characterized by an increase in the plasma level of IgG (1) and in LPS-induced IL-6 release and, by a reduction in PHA-induced IL-10 and IFN release, associated with a reduced IFN/IL-4 ratio. |
31(0,1,1,1) | Details |