| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | propanil |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18214888 | Rankin GO, Racine C, Sweeney A, Kraynie A, Anestis DK, Barnett JB: In vitro nephrotoxicity induced by propanil. . Environ Toxicol. 2008 Aug;23(4):435-42. In IRCC pretreated with an antioxidant, cytochrome P450 (CYP) inhibitor, monooxygenase activity modulator, or cyclooxygenase inhibitor before propanil exposure (1.0 mM; 120 min), only piperonyl butoxide (0.1 mM), a CYP inhibitor, pretreatment decreased propanil cytotoxicity. |
31(0,1,1,1) | Details |
| 2315923 | McMillan DC, Leakey JE, Arlotto MP, McMillan JM, Hinson JA: Metabolism of the arylamide herbicide propanil. Toxicol Appl Pharmacol. 1990 Mar 15;103(1):102-12. Propanil (3,4-dichloropropionanilide) is an arylamide herbicide that has been reported to be contaminated with the cytochrome P450 enzyme inducers 3,3',4,4'-tetrachloroazobenzene (TCAB) and 3,3',4,4'-tetrachloroazoxybenzene (TCAOB), which are structural analogs of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). |
12(0,0,2,2) | Details |
| 18835618 | Takeuchi S, Iida M, Yabushita H, Matsuda T, Kojima H: In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron. Chemosphere. 2008 Dec;74(1):155-65. Epub 2008 Oct 5. |
7(0,0,1,2) | Details |
| 11986682 | : NTP Technical Report on the Toxicity Studies of 3,3',4,4'-Tetrachloroazobenzene (CAS No. 14047-09-7) Administered by Gavage to F344/N Rats and B6C3F1 Mice. Toxic Rep Ser. 1998 Nov;65:1-F6. 3,3',4,4'-Tetrachloroazobenzene is not commercially manufactured but is formed as an unwanted byproduct in the manufacture of 3,4-dichloroaniline and its herbicidal derivatives Propanil (R), Linuron (R), and Diuron (R). In addition to histopathology, evaluations included hematology (rats only), clinical chemistry, thyroid hormone analyses (rats only), cytochrome P (450) 1A immunohistochemical staining in the liver (rats only), and assessments of male reproductive endpoints and estrous cycle length. |
3(0,0,0,3) | Details |
| 10918358 | Kaya B, Creus A, Yanikoglu A, Cabre O, Marcos R: Use of the Drosophila wing spot test in the genotoxicity testing of different herbicides. Environ Mol Mutagen. 2000;36(1):40-6. Four herbicides, namely propanil, maleic hydrazide, and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), were investigated for genotoxicity in the wing spot test of Drosophila melanogaster. The HB cross uses flies characterized by an increased cytochrome P-450-dependent bioactivation capacity, which permits a more efficient biotransformation of promutagens and procarcinogens. |
1(0,0,0,1) | Details |