Name | PTP1B |
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Synonyms | PTP 1B; PTP1B; PTPN 1; PTPN1; Protein tyrosine phosphatase 1B; Tyrosine protein phosphatase non receptor type 1; Protein tyrosine phosphatase 1Bs; Tyrosine protein phosphatase non receptor type 1s |
Name | nitrostyrene |
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CAS | 4-(2-nitro-1-propenyl)phenyl thiocyanate |
PubMed | Abstract | RScore(About this table) | |
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15554709 | Park J, Pei D: trans-Beta-nitrostyrene derivatives as slow-binding inhibitors of protein tyrosine phosphatases. Biochemistry. 2004 Nov 30;43(47):15014-21. In this work, trans-beta-nitrostyrene (TBNS) and its derivatives are found to be slow-binding inhibitors against protein tyrosine phosphatases PTP1B, SHP-1, and Yop with moderate potencies (K (I*) = 1-10 microM). |
82(1,1,1,2) | Details |