Protein Information

Name PTB1
Synonyms 57 kDa RNA binding protein PPTB1; 57 kDa RNA binding protein PPTB 1; HNRNPI; HNRPI; Heterogeneous nuclear ribonucleoprotein I; Heterogeneous nuclear ribonucleoprotein polypeptide 1; PTB; PTB 1…

Compound Information

Name nitrostyrene
CAS 4-(2-nitro-1-propenyl)phenyl thiocyanate

Reference List

PubMed Abstract RScore(About this table)
17136318 Werner JM, Eger K, Jurgen Steinfelder H: Comparison of the rapid pro-apoptotic effect of trans-beta-nitrostyrenes with delayed apoptosis induced by the standard agent 5-fluorouracil in colon cancer cells. Apoptosis. 2007 Jan;12(1):235-46.

Trans-beta-nitrostyrene (TBNS) has been reported to be a potent inhibitor of protein phosphatases PTB1 and PP2A and to display a pro-apoptotic effect even in multidrug resistant tumour cells.
81(1,1,1,1) Details