| 2893460 |
Colacci A, Grilli S, Lattanzi G, Prodi G, Paola Turina M, Cantelli Forti G, Mazzullo M: The covalent binding of 1,1,2,2-tetrachloroethane to macromolecules of rat and mouse organs. Teratog Carcinog Mutagen. 1987;7(5):465-74.
In in vitro cell-free systems, 1,1,2,2-tetrachloroethane was bioactivated by mixed-function oxidase (s) and glutathione-S-transferase (s) (GSH-T) from microsomal and cytosolic fractions of rat and mouse liver and, to a lesser extent, of mouse lung. |
81(1,1,1,1) |
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| 1317068 |
Paolini M, Sapigni E, Mesirca R, Pedulli GF, Corongiu FP, Dessi MA, Cantelli-Forti G: On the hepatotoxicity of 1,1,2,2-tetrachloroethane. . Toxicology. 1992;73(1):101-15.
As phase II markers, epoxide hydrolase (approximately 35% loss), UDP-glucuronosyl transferase (approximately 42% loss) and to a lesser extent glutathione S-transferase (approximately 17% loss) were all affected. |
1(0,0,0,1) |
Details |