| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | TEPP |
|---|---|
| CAS | tetraethyl diphosphate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3965707 | Herrador MM, Saenz de Buruaga J, Suarez MD: Reactivators of organophosphorus-inhibited acetylcholinesterase. 1. J Med Chem. 1985 Jan;28(1):146-9. 4-[(Hydroxyimino) methyl]-3-methylimidazolium iodides were prepared and tested for their reactivating potency on acetylcholinesterase inhibited by tetraethyl (TEPP). |
83(1,1,1,3) | Details |
| 14139940 | RUNTI C, STENER A, SOTTOCASA G, PUGLIARELLO MC: [ON SOME NEW QUATERNARY DERIVATIVES OF -2- REACTIVATORS OF ACETYLCHOLINESTERASE INHIBITED BY TEPP.] Boll Chim Farm. 1964 Feb;103:103-14. |
81(1,1,1,1) | Details |
| 13489171 | HOBBIGER F: Protection against the lethal effects of organophosphates by -2- methiodide. Br J Pharmacol Chemother. 1957 Dec;12(4):438-46. P-2-AM on the phosphorylated true cholinesterase in brain (experiments with TEPP and E 600) was negligible. |
37(0,1,2,2) | Details |
| 16515465 | Kuca K, Juna D, Musilek K: Structural requirements of acetylcholinesterase reactivators. Mini Rev Med Chem. 2006 Mar;6(3):269-77. Nerve agents (sarin, soman, cyclosarin, tabun and VX agent) and pesticides (paraoxon, chlorpyrifos, TEPP) represent extremely toxic group of organophosphorus compounds (OPCs). |
8(0,0,0,8) | Details |
| 16481169 | Srinivas Rao C, Venkateswarlu V, Achaiah G: Quaternary salts of 4,3' and 4,4' bis-pyridinium monooximes. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2134-8. Epub 2006 Feb 14. Their ability to reactivate tetraethylpyrophosphate (TEPP) inhibited mouse total brain cholinesterase was investigated and compared with the conventional oxime 2-pyridinealdoxime chloride (2-PAM). Mouse brain homogenate was used as the source of acetylcholinesterase. |
2(0,0,0,2) | Details |
| 4035678 | Volpe LS, Biagioni TM, Marquis JK: In vitro modulation of bovine caudate muscarinic receptor number by organophosphates and carbamates. Toxicol Appl Pharmacol. 1985 Apr;78(2):226-34. Diethyl-p-nitrophenyl (paraoxon; PX), dichlorvos (DDVP), and tetraethyl (TEPP) were demonstrated to be weak noncompetitive receptor inactivators. |
0(0,0,0,0) | Details |