Name | P450 4 |
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Synonyms | CP12; CYP1A2; CYPIA 2; CYPIA2; Cytochrome P450 1A2; Dioxin inducible P3 450; P(3)450; P3 450… |
Name | gibberellins |
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CAS | gibberellins |
PubMed | Abstract | RScore(About this table) | |
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11472927 | Tudzynski B, Hedden P, Carrera E, Gaskin P: The P450-4 gene of Gibberella fujikuroi encodes ent-kaurene oxidase in the biosynthesis pathway. Appl Environ Microbiol. 2001 Aug;67(8):3514-22. |
7(0,0,0,7) | Details |
15746349 | Malonek S, Rojas MC, Hedden P, Gaskin P, Hopkins P, Tudzynski B: Functional characterization of two cytochrome P450 monooxygenase genes, P450-1 and P450-4, of the gene cluster in Fusarium proliferatum (Gibberella fujikuroi MP-D). Appl Environ Microbiol. 2005 Mar;71(3):1462-72. |
2(0,0,0,2) | Details |
12581353 | Mihlan M, Homann V, Liu TW, Tudzynski B: AREA directly mediates regulation of biosynthesis in Gibberella fujikuroi, but its activity is not affected by NMR. Mol Microbiol. 2003 Feb;47(4):975-91. The binding of AREA was analysed in more detail using the promoter of one of the GA-biosynthesis genes encoding the ent-kaurene oxidase (P450-4). |
2(0,0,0,2) | Details |
16204516 | Malonek S, Rojas MC, Hedden P, Hopkins P, Tudzynski B: Restoration of production in Fusarium proliferatum by functional complementation of enzymatic blocks. Appl Environ Microbiol. 2005 Oct;71(10):6014-25. Members of Fusarium proliferatum, the closest related species, have lost the ability to produce GAs as a result of the accumulation of several mutations in the coding and 5' noncoding regions of genes P450-4 and P450-1, both encoding cytochrome P450 monooxygenases, resulting in metabolic blocks at the early stages of GA biosynthesis. |
1(0,0,0,1) | Details |
15925394 | Malonek S, Bomke C, Bornberg-Bauer E, Rojas MC, Hedden P, Hopkins P, Tudzynski B: Distribution of production in the Gibberella fujikuroi species complex. Phytochemistry. 2005 Jun;66(11):1296-311. They produce a variety of secondary metabolites, such as fumonisins, fusaproliferin, moniliformin, beauvericin, fusaric acid, and gibberellins (GAs), a group of plant hormones. We used two new molecular marker genes, P450-4 from the GA gene cluster, and cpr, encoding the highly conserved NADPH cytochrome P450 reductase to study phylogenetic relationships within the G. fujikuroi species complex. |
biosynthetic genes and 1(0,0,0,1) | Details |
15037621 | Malonek S, Rojas MC, Hedden P, Gaskin P, Hopkins P, Tudzynski B: The NADPH-cytochrome P450 reductase gene from Gibberella fujikuroi is essential for biosynthesis. J Biol Chem. 2004 Jun 11;279(24):25075-84. Epub 2004 Mar 22. Northern blot analysis revealed co-regulated expression of the cpr-Gf gene and the GA biosynthetic genes P450-1, P450-2, P450-4 under GA production conditions starvation). The fungus Gibberella fujikuroi is used for the commercial production of gibberellins (GAs), which it produces in very large quantities. |
1(0,0,0,1) | Details |