Name | Acetylcholinesterase |
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Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
Name | carvone |
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CAS | 2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one |
PubMed | Abstract | RScore(About this table) | |
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19412756 | Abdelgaleil SA, Mohamed MI, Badawy ME, El-arami SA: Fumigant and contact toxicities of monoterpenes to Sitophilus oryzae (L.) and Tribolium castaneum (Herbst) and their inhibitory effects on acetylcholinesterase activity. J Chem Ecol. 2009 May;35(5):518-25. Epub 2009 May 5. In vitro inhibition studies of AChE from adults of S. oryzae showed that most effectively inhibited enzyme activity at the two tested concentrations (0.01 and 0.05 M) followed by 1-8- (-)- and (L)-fenchone. 1-8- was the most potent inhibitor of AChE activity from T. castaneum larvae followed by (-)-carvone and (-)- |
33(0,1,1,3) | Details |
18810999 | Orhan I, Kartal M, Kan Y, Sener B: Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. Z Naturforsch C. 2008 Jul-Aug;63(7-8):547-53. We have tested acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of nineteen essential oils obtained from cultivated plants, namely one from Anethum graveolens L. (organic fertilizer), two from Foeniculum vulgare Mill. collected at fully-mature and flowering stages (organic fertilizer), two from Melissa officinalis L. (cultivated using organic and chemical fertilizers), two from Mentha piperita L. and M. spicata L. (organic fertilizer), two from Lavandula officinalis Chaix ex Villars (cultivated using organic and chemical fertilizers), two from Ocimum basilicum L. (green and purple-leaf varieties cultivated using only organic fertilizer), four from Origanum onites L., O. vulgare L., O. munitiflorum Hausskn., and O. majorana L. (cultivated using organic fertilizer), two from Salvia sclarea L. (organic and chemical fertilizers), one from S. officinalis L. (organic fertilizer), and one from Satureja cuneifolia Ten. (organic fertilizer) by a spectrophotometric method of Ellman using ELISA microplate-reader at 1 mg/ml concentration. In addition, a number of single components widely encountered in most of the essential oils 4-allyl anisole, (-)-carvone, dihydrocarvone, (-)-phencone, cuminyl cumol, 4-isopropyl benzaldehyde, trans-anethole, camphene, iso-borneol, (-)-borneol, L-bornyl 2-decanol, 2-heptanol, methyl-heptanol, nerol, iso-pulegol, citral, citronellal, citronellol, linalool, alpha-pinene, beta-pinene, piperitone, iso-menthone, menthofurane, linalyl oxide, linalyl ester, geranyl ester, carvacrol, vanilline, and was also screened for the same activity in the same manner. |
1(0,0,0,1) | Details |