Protein Information

Name CYP1A2
Synonyms CP12; CYP1A2; CYPIA 2; CYPIA2; Cytochrome P450 1A2; Dioxin inducible P3 450; P(3)450; P3 450…

Compound Information

Name carvone
CAS 2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one

Reference List

PubMed Abstract RScore(About this table)
15618705 Shimada T, Shindo M, Miyazawa M: Species differences in the metabolism of (+)- and (-)-limonenes and their metabolites, carveols and carvones, by cytochrome P450 enzymes in liver microsomes of mice, rats, guinea pigs, rabbits, dogs, monkeys, and humans. Drug Metab Pharmacokinet. 2002;17(6):507-15.

Reconstituted monooxygenase systems containing purified rabbit CYP1A2 and 2B4 and NADPH-P450 reductase were found to catalyze (+)-limonene to (+)-carveol, (+)-carvone, and (+)-perillyl alcohol, being more active with CYP2B4.
31(0,1,1,1) Details