| Name | lipoprotein lipase |
|---|---|
| Synonyms | LIPD; LPL; LPL protein; Lipase D; Lipoprotein lipase; Lipoprotein lipase precursor; Lipoprotein lipase variant; LPL proteins… |
| Name | sodium chlorate |
|---|---|
| CAS | sodium chlorate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9359432 | Mast AE, Higuchi DA, Huang ZF, Warshawsky I, Schwartz AL, Broze GJ Jr: Glypican-3 is a binding protein on the HepG2 cell surface for tissue factor pathway inhibitor. Biochem J. 1997 Oct 15;327 ( Pt 2):577-83. In addition, when the sulphation of glycosaminoglycans (GAGs) is prevented by growing the HepG2 cells in the presence of 30 mM sodium chlorate, TFPI binding is unaffected, whereas the binding of bovine lipoprotein lipase, a protein known to associate with cell-surface GAGs, falls to 50% of control levels. |
31(0,1,1,1) | Details |
| 1885587 | Hoogewerf AJ, Cisar LA, Evans DC, Bensadoun A: Effect of on the sulfation of lipoprotein lipase and heparan sulfate proteoglycans. J Biol Chem. 1991 Sep 5;266(25):16564-71. To test further this hypothesis, the binding capacity of the plasma membrane for the lipase was decreased by inhibiting the sulfation of glycosaminoglycans with sodium chlorate, an inhibitor of adenyltransferase. |
6(0,0,0,6) | Details |
| 7605368 | Sehayek E, Olivecrona T, Bengtsson-Olivecrona G, Vlodavsky I, Levkovitz H, Avner R, Eisenberg S: Binding to is a major event during catabolism of lipoprotein lipase by HepG2 and other cell cultures. Atherosclerosis. 1995 Apr 7;114(1):1-8. LPL metabolism in HepG2 cells was characterized by a high capacity to degrade the enzyme, an extremely high sensitivity to and was inhibited by 60%-70% after treatment of the cells with sodium chlorate and heparinase (but not chondroitinase). |
2(0,0,0,2) | Details |
| 9560300 | Halvorsen B, Aas UK, Kulseth MA, Drevon CA, Christiansen EN, Kolset SO: Proteoglycans in macrophages: characterization and possible role in the cellular uptake of lipoproteins. Biochem J. 1998 May 1;331 ( Pt 3):743-52. Addition of lipoprotein lipase increased the uptake of oxidized 125I-TC-LDL 1.7 times and the uptake of native 125I-TC-LDL 2.1 times. |
1(0,0,0,1) | Details |
| 12810721 | Fuki IV, Blanchard N, Jin W, Marchadier DH, Millar JS, Glick JM, Rader DJ: Endogenously produced endothelial lipase enhances binding and cellular processing of plasma lipoproteins via heparan sulfate proteoglycan-mediated pathway. J Biol Chem. 2003 Sep 5;278(36):34331-8. Epub 2003 Jun 16. Endothelial lipase (EL) is a new member of the triglyceride lipase gene family, which includes lipoprotein lipase (LpL) and hepatic lipase (HL). Inhibition of proteoglycan sulfation by sodium chlorate or incubation of cells with labeled lipoproteins in the presence of (100 microg/ml) abolished bridging effects of EL. |
1(0,0,0,1) | Details |
| 15539309 | Hagen E, Myhre AM, Smeland S, Halvorsen B, Norum KR, Blomhoff R: Uptake of in macrophages from physiologic transport proteins: role of retinol-binding protein and chylomicron remnants. J Nutr Biochem. 1999 Jun;10(6):345-52. In addition, lipoprotein lipase increased the binding of chylomicron remnant [(3) H] retinyl esters by approximately 30% and the uptake of chylomicron remnant [(3) H] by more than 300%. Furthermore, because sodium chlorate reduced binding with 40% and uptake with 55%, the results suggest that proteoglycans are involved in the uptake. |
1(0,0,0,1) | Details |