Protein Information

Name Chondroitin sulfate proteoglycans
Synonyms BCAN; BEHAB; Brain enriched hyaluronan binding protein; Brevican; Brevican core protein; Brevican core protein precursor; CSPG 7; CSPG7…

Compound Information

Name sodium chlorate
CAS sodium chlorate

Reference List

PubMed Abstract RScore(About this table)
9915576 Kubota Y, Morita T, Kusakabe M, Sakakura T, Ito K: Spatial and temporal changes in chondroitin sulfate distribution in the sclerotome play an essential role in the formation of migration patterns of mouse neural crest cells. Dev Dyn. 1999 Jan;214(1):55-65.

Furthermore, their migration patterns are altered in embryos treated with the inhibitors of chondroitin sulfate proteoglycan biosynthesis, sodium chlorate, and beta-D-xyloside.
32(0,1,1,2) Details
12922982 Shannon JM, McCormick-Shannon K, Burhans MS, Shangguan X, Srivastava K, Hyatt BA: Chondroitin sulfate proteoglycans are required for lung growth and morphogenesis in vitro. Am J Physiol Lung Cell Mol Physiol. 2003 Dec;285(6):L1323-36. Epub 2003 Aug 15.

We have investigated the role of sulfated PGs in early rat lung development by treating cultured tissues with 30 mM sodium chlorate, a global inhibitor of PG sulfation.
1(0,0,0,1) Details
8096145 Patel M, Yanagishita M, Roderiquez G, Bou-Habib DC, Oravecz T, Hascall VC, Norcross MA: Cell-surface heparan sulfate proteoglycan mediates HIV-1 infection of T-cell lines. AIDS Res Hum Retroviruses. 1993 Feb;9(2):167-74.

HIV-1-susceptible lymphoblastic T-cell lines, MT-4 and H9, were analyzed for proteoglycan synthesis and found to make heparan sulfate (HS) and chondroitin sulfate proteoglycans.
Sulfation of glycosaminoglycans HS chains was critical to viral entry as shown by inhibition of viral infection with sodium chlorate and its specific reversal with exogenous sulfate addition.
1(0,0,0,1) Details