Name | phosphodiesterase |
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Synonyms | CAMP specific phosphodiesterase variant PDE4A 10; CAMP specific phosphodiesterase variant TM3; CAMP specific phosphodiesterase; Cyclic AMP phosphodiesterase PDE4A11; Cyclic AMP specific phosphodiesterase HSPDE4A10; DPDE 2; DPDE2; PDE 4… |
Name | sodium chlorate |
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CAS | sodium chlorate |
PubMed | Abstract | RScore(About this table) | |
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17261351 | Levallet G, Levallet J, Bonnamy PJ: Alterations in proteoglycan synthesis selectively impair FSH-induced particulate cAMP-phosphodiesterase 4 (PDE4) activation in immature rat Sertoli cells. Biochim Biophys Acta. 2007 Apr;1770(4):638-48. Epub 2006 Dec 21. FSH-induced upregulation of cAMP-PDE4 activities was decreased in cultured Sertoli cells when alteration of cell proteoglycans (PGs) metabolism was simultaneously induced either by para-nitrophenyl beta-d-xyloside (PNPX) or by sodium chlorate. |
35(0,1,1,5) | Details |
18372231 | Levallet G, Levallet J, Bonnamy PJ: FSH-induced phosphoprotein phosphatase 2A-mediated deactivation of particulate phosphodiesterase-4 activities is abolished after alteration in proteoglycan synthesis in immature rat Sertoli cells. J Endocrinol. 2008 Apr;197(1):45-54. Both the FSH-induced increase in recruitment/activation of particulate PP2A and the subsequent deactivation of particulate PDE4 were abolished when Sertoli cell proteoglycans (PGs) synthesis was altered by sodium chlorate. |
33(0,1,1,3) | Details |
10232659 | Phamantu NT, Fagnen G, Godard F, Bocquet J, Bonnamy PJ: Sodium chlorate induces undersulfation of cellular proteoglycans and increases in FSH-stimulated production in immature rat Sertoli cells. J Androl. 1999 Mar-Apr;20(2):241-50. Addition of phosphodiesterase inhibitors (MIX or Ro20-1724) decreased the magnitude of the effect on FSH-stimulated steroidogenesis, suggesting that part of chlorate's effect on steroidogenesis resulted from a decrease in cyclic 3',5'- (cAMP)-specific phosphodiesterase activity. |
2(0,0,0,2) | Details |
15144459 | Feistritzer C, Kaneider NC, Sturn DH, Wiedermann CJ: Syndecan-4-dependent migration of human eosinophils. . Clin Exp Allergy. 2004 May;34(5):696-703. The effects of anti-thrombin III were abolished by pre-treating cells with heparinase-1, chondroitinase, sodium chlorate and anti-syndecan-4 antibodies. Functional responses were also abrogated by inhibition of protein kinase C, phosphatidylinositol 3-kinase and phosphodiesterase. |
1(0,0,0,1) | Details |