| Name | P selectin |
|---|---|
| Synonyms | CD62; CD62P; CD62P antigen; GMP 140; GMP140; GMRP; GRMP; Granule membrane protein 140… |
| Name | sodium chlorate |
|---|---|
| CAS | sodium chlorate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11821431 | Kawashima H, Atarashi K, Hirose M, Hirose J, Yamada S, Sugahara K, Miyasaka M: Oversulfated / sulfates containing GlcAbeta1/IdoAalpha1-3GalNAc (4,6-O-disulfate) interact with L- and P-selectin and chemokines. J Biol Chem. 2002 Apr 12;277(15):12921-30. Epub 2002 Jan 30. Using a metabolic inhibitor of sulfation, sodium chlorate, we show that the interactions of the CS/DS chains of versican with L- and P-selectin and chemokines are sulfation-dependent but the interaction with CD44 is sulfation-independent. |
36(0,1,1,6) | Details |
| 17177829 | Sinha RK, Yang G, Alexander C, Mage RG: De novo expression of MECA-79 glycoprotein-determinant on developing B lymphocytes in gut-associated lymphoid tissues. Immunology. 2006 Dec;119(4):461-9. Alternatively, because we found that lymphatic endothelium in the thymus-dependent area of appendix, a site for lymphocyte exit, expressed P-selectin (CD62P), interaction of the MECA-79 determinant on B cells with CD62P may have a role in the exit of B lymphocytes from rabbit appendix. Binding of the mAb to B lymphocytes was sensitive to enzyme treatment with O-sialoglycoprotease and expression was partially inhibited by sodium chlorate, a metabolic inhibitor of sulphation. |
1(0,0,0,1) | Details |
| 11823498 | Ma YQ, Geng JG: Obligatory requirement of sulfation for P-selectin binding to human salivary gland carcinoma Acc-M cells and breast carcinoma ZR-75-30 cells. J Immunol. 2002 Feb 15;168(4):1690-6. Sodium chlorate also inhibited the P-selectin precipitation of the 160-, 54-, and 36-kDa molecules from the cell surface of Acc-M cells. |
89(1,1,1,9) | Details |
| 17043066 | Garcia J, Callewaert N, Borsig L: P-selectin mediates metastatic progression through binding to sulfatides on tumor cells. Glycobiology. 2007 Feb;17(2):185-96. Epub 2006 Oct 16. Metabolic inhibition of sulfation by incubation of cells with sodium chlorate almost completely abrogated P-selectin binding. |
38(0,1,1,8) | Details |
| 9671523 | Kaytes PS, Geng JG: P-selectin mediates adhesion of the human melanoma cell line NKI-4: identification of glycoprotein ligands. Biochemistry. 1998 Jul 21;37(29):10514-21. Surprisingly, we found that sodium chlorate, a sulfation inhibitor, did not inhibit the binding of P-selectin to NKI-4 cells and that [35S]- did not label the NKI-4 cell ligands. |
5(0,0,0,5) | Details |