| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | spinosad |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17665366 | Reyes M, Franck P, Charmillot PJ, Ioriatti C, Olivares J, Pasqualini E, Sauphanor B: Diversity of insecticide resistance mechanisms and spectrum in European populations of the codling moth, Cydia pomonella. Pest Manag Sci. 2007 Sep;63(9):890-902. Resistances to azinphos-methyl, diflubenzuron, spinosad, tebufenozide and thiacloprid were significantly correlated with mixed-function oxidase activity, while increased glutathione-S-transferase and reduced non-specific esterase activities were correlated with resistance to azinphos-methyl and emamectin, respectively. |
81(1,1,1,1) | Details |
| 17675233 | Perez-Pertejo Y, Reguera RM, Ordonez D, Balana-Fouce R: Alterations in the -redox balance induced by the bio-insecticide Spinosad in CHO-K1 and Vero cells. Ecotoxicol Environ Saf. 2008 Jun;70(2):251-8. Epub 2007 Aug 1. At concentrations equivalent to its NRU (20), NRU (10) and NRU (5) Spinosad caused significant alterations in the -redox cycle in the form of significant decrease in total and large increase in peroxidase activity, little induction of glutathione reductase, and significant decline of glutathione S-transferase activities. |
6(0,0,1,1) | Details |
| 17098168 | Willoughby L, Chung H, Lumb C, Robin C, Batterham P, Daborn PJ: A comparison of Drosophila melanogaster detoxification gene induction responses for six insecticides, and phenobarbital. Insect Biochem Mol Biol. 2006 Dec;36(12):934-42. Epub 2006 Sep 23. Mutations leading to changes in expression levels or substrate specificities of cytochrome P450 (P450), glutathione-S-transferase (GST) and esterase genes have been linked to many cases of resistance with the responsible enzyme shown to utilize the insecticide as a substrate. The insecticides spinosad, diazinon, nitenpyram, lufenuron and dicyclanil did not induce any P450, GST or esterase gene expression after a short exposure to high lethal concentrations of insecticide. |
1(0,0,0,1) | Details |
| 19548293 | Achaleke J, Martin T, Ghogomu RT, Vaissayre M, Brevault T: Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. Pest Manag Sci. 2009 Oct;65(10):1147-54. CONCLUSION: Knowledge of the mechanisms involved in pyrethroid resistance and the lack of cross-resistance to spinosad and indoxacarb is a key to devising new resistance management strategies aimed at restoring the efficacy of pyrethroid-based programmes. |
0(0,0,0,0) | Details |
| 19533589 | Wang D, Qiu X, Ren X, Zhang W, Wang K: Effects of spinosad on Helicoverpa armigera (Lepidoptera: Noctuidae) from China: tolerance status, synergism and enzymatic responses. Pest Manag Sci. 2009 Sep;65(9):1040-6. |
0(0,0,0,0) | Details |