Name | D lactate dehydrogenase |
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Synonyms | D lactate dehydrogenase; DLD; LDHD; Lactate dehydrogenase D; Lactate dehydrogenase Ds |
Name | oxamate |
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CAS | hexyl 2-(diethylamino)-2-oxoacetate |
PubMed | Abstract | RScore(About this table) | |
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4579004 | Reeves JP, Hong JS, Kaback HR: Reconstitution of transport in membrane vesicles from a D-lactate dehydrogenase mutant of Escherichia coli. Proc Natl Acad Sci U S A. 1973 Jul;70(7):1917-21. |
-dependent 4(0,0,0,4) | Details |
6402502 | Mueller PR, Collins ML: Identification of two distinct lactate dehydrogenases in Rhodospirillum rubrum. J Bacteriol. 1983 Mar;153(3):1562-6. Crossed immunoelectrophoretic analysis revealed two antigenically distinct enzymes that were further distinguished by specificity for d- and l-stereoisomers of lactate and by the sensitivity of the d-lactate dehydrogenase to inhibition by oxamate and |
81(1,1,1,1) | Details |
9399585 | Taguchi H, Ohta T, Matsuzawa H: Involvement of interaction between the catalytic and substrate for the D-lactate dehydrogenase catalysis. J Biochem. 1997 Oct;122(4):802-9. The replacement of Arg-235 with Gln destabilized the inhibitory binding of oxamate much more than that of or and the Arg to substitution specifically diminished only oxamate binding. |
-264 and Arg-235 in the essential 2(0,0,0,2) | Details |
168830 | Sanchez JJ, Palleroni NJ, Doudoroff M: Lactate dehydrogenases in cyanobacteria. Arch Microbiol. 1975 Jun 20;104(1):57-65. The D-lactate dehydrogenase of one strain (Synechococcus 6716) was partially purified and its properties were studied. |
1(0,0,0,1) | Details |
11396932 | Jasso-Chavez R, Torres-Marquez ME, Moreno-Sanchez R: The Membrane-bound L- and D-lactate dehydrogenase activities in mitochondria from Euglena gracilis. Arch Biochem Biophys. 2001 Jun 15;390(2):295-303. Oxamate was a competitive inhibitor against both L- and |
1(0,0,0,1) | Details |
7961609 | Taguchi H, Ohta T: Essential role of substrate-binding of Lactobacillus plantarum D-lactate dehydrogenase. J Biochem. 1994 May;115(5):930-6. Both the mutant enzymes showed a marked resistance to by which the wild-type enzyme is rapidly inactivated unless and oxamate are present. |
235 in the 1(0,0,0,1) | Details |