| Name | transferase |
|---|---|
| Synonyms | 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80… |
| Name | oxamate |
|---|---|
| CAS | hexyl 2-(diethylamino)-2-oxoacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19341298 | Zeczycki TN, St Maurice M, Jitrapakdee S, Wallace JC, Attwood PV, Cleland WW: Insight into the carboxyl transferase domain mechanism of pyruvate carboxylase from Rhizobium etli. Biochemistry. 2009 May 26;48(20):4305-13. Furthermore, the partial inhibition of the T882A-catalyzed BC domain reactions by oxamate and further supports the critical role of Thr882 in the transfer between and in the carboxyl transferase domain. |
114(1,2,2,4) | Details |
| 20230056 | Duangpan S, Jitrapakdee S, Adina-Zada A, Byrne L, Zeczycki TN, St Maurice M, Cleland WW, Wallace JC, Attwood PV: Probing the Catalytic Roles of Arg548 and Gln552 in the Carboxyl Transferase Domain of the Rhizobium etli Pyruvate Carboxylase by Site-Directed Mutagenesis. Biochemistry. 2010 Mar 25. The effects of oxamate on the catalysis in the biotin carboxylase domain by the R548K and Q552N mutants were similar to those on the catalysis of reactions by the wild-type enzyme. |
3(0,0,0,3) | Details |
| 15030490 | Sueda S, Islam MN, Kondo H: Protein engineering of pyruvate carboxylase: investigation on the function of and the quaternary structure. Eur J Biochem. 2004 Apr;271(7):1391-400. Pyruvate carboxylase (PC) from Bacillus thermodenitrificans was engineered in such a way that the polypeptide chain was divided into two, between the biotin carboxylase (BC) and carboxyl transferase (CT) domains. The two proteins thus formed, PC-(BC) and PC-(CT+BCCP), retained their catalytic activity as assayed by -dependent ATPase and oxamate-dependent decarboxylation, for the former and the latter, respectively. |
1(0,0,0,1) | Details |