| Name | cytochrome P450 1A1 |
|---|---|
| Synonyms | AHH; AHRR; Arylhydrocarbon hydroxylase; CP11; CYP 1; CYP1; CYP1A1; CYPIA 1… |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11312644 | Sieben S, Hertl M, Al Masaoudi T, Merk HF, Blomeke B: Characterization of T cell responses to fragrances. Toxicol Appl Pharmacol. 2001 May 1;172(3):172-8. Interestingly, stimulation of eugenol and was increased in the presence of antigen-modified human liver microsomes (CYP450) or recombinant CYP1A1 in five of seven cases. |
81(1,1,1,1) | Details |
| 15576237 | Sakano K, Inagaki Y, Oikawa S, Hiraku Y, Kawanishi S: -mediated oxidative DNA damage induced by eugenol: possible involvement of O-demethylation. Mutat Res. 2004 Dec 31;565(1):35-44. Eugenol induced Cu (II)-mediated DNA damage in the presence of cytochrome P450 (CYP) 1A1, 1A2, 2C9, 2D6, or 2E1. |
81(1,1,1,1) | Details |
| 17275817 | Han EH, Hwang YP, Jeong TC, Lee SS, Shin JG, Jeong HG: Eugenol inhibit 7,12-dimethylbenz [a] anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD (P) H:quinone oxidoreductase. FEBS Lett. 2007 Feb 20;581(4):749-56. Epub 2007 Jan 25. CYP1A1 and CYP1B1 activity, which catalyze the biotransformation of DMBA, were strongly inhibited by eugenol. |
31(0,1,1,1) | Details |