Name | caspase (protein family or complex) |
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Synonyms | caspase; caspases |
Name | eugenol |
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CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
PubMed | Abstract | RScore(About this table) | |
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17233906 | Pisano M, Pagnan G, Loi M, Mura ME, Tilocca MG, Palmieri G, Fabbri D, Dettori MA, Delogu G, Ponzoni M, Rozzo C: Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells. Mol Cancer. 2007 Jan 18;6:8. Cytotoxic activity and apoptosis induced by treating melanoma cells with eugenol-related biphenyls was partially dependent by caspase activation. |
31(0,1,1,1) | Details |
19389048 | Fujimoto A, Sakanashi Y, Matsui H, Oyama T, Nishimura Y, Masuda T, Oyama Y: Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: potent cytotoxicity of The compounds examined in this study were (+)- sesamol, and eugenol. In the presence of benzyloxycarbonyl-Val- -Asp (OMe) fluoromethylketone (Z-VAD-FMK), a pan-inhibitor of caspases, the -induced increase in the population of cells with hypodiploidal DNA was partially inhibited. |
to normal cells. Basic Clin Pharmacol Toxicol. 2009 Jun;104(6):455-62. Epub 2009 Mar 11.1(0,0,0,1) | Details |
10871845 | Chainy GB, Manna SK, Chaturvedi MM, Aggarwal BB: Anethole blocks both early and late cellular responses transduced by tumor necrosis factor: effect on NF-kappaB, AP-1, JNK, MAPKK and apoptosis. Oncogene. 2000 Jun 8;19(25):2943-50. In addition, anethole abrogated TNF-induced apoptosis as measured by both caspase activation and cell viability. The anethole analogues eugenol and also blocked TNF signaling. |
1(0,0,0,1) | Details |