| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | tetrachlorvinphos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 646783 | Plapp FW Jr, Tripathi RK: Biochemical genetics of altered acetylcholinesterase resistance to insecticides in the house fly. Biochem Genet. 1978 Feb;16(1-2):1-11. Resistance to the organophosphate insecticide tetrachlorvinphos was examined in a house fly (Musca domestica L.) strain with an altered acetylcholinesterase (AChE) of decreased sensitivity to inhibition by the insecticide. |
65(0,2,2,5) | Details |
| 687628 | Tripathi RK, Telford JN, O'Brien RD: Molecular and structural characteristics of house fly brain acetylcholinesterase. Biochim Biophys Acta. 1978 Jul 7;525(1):103-11. Acetylcholinesterase (acetylcholine hydrolase, EC 3.1.1.7) from the brains of house flies (Musca domestica L., tetrachlorvinphos-resistant strain) was examined for molecular and structural features, including molecular weight, Stokes radii, partial specific volumes, sedimentation coefficients and frictional ratios. |
7(0,0,1,2) | Details |
| 18166255 | Karanth S, Holbrook T, MacAllister C, Pope CN: Selective inhibition of butyrylcholinesterase in vivo in horses by the feed-through larvacide Equitrol. Regul Toxicol Pharmacol. 2008 Mar;50(2):200-5. Epub 2007 Nov 28. The organophosphate insecticide tetrachlorvinphos (TCVP, Rabon) is the active ingredient in "feed-through" larvacides (e.g., Equitrol) for fly control around horse stables. As with other organophosphates, TCVP elicits toxicity by inhibiting acetylcholinesterase, leading to accumulation of the neurotransmitter and cholinergic signs. |
4(0,0,0,4) | Details |
| 18163527 | Kozaki T, Kimmelblatt BA, Hamm RL, Scott JG: Comparison of two acetylcholinesterase gene cDNAs of the lesser mealworm, Alphitobius diaperinus, in insecticide susceptible and resistant strains. Arch Insect Biochem Physiol. 2008 Mar;67(3):130-8. Partial cDNA sequences of the Alphitobius Ace genes were compared between two tetrachlorvinphos resistant (Kennebec and Waycross) and one susceptible strain of beetles. |
3(0,0,0,3) | Details |
| 1364360 | Ogawa Y, Suzuki S, Takada K, Sai K, Kamata E, Umemura T, Kaneko T, Kurokawa Y: [Twenty-eight-day repeated dose toxicity test for tetrachlorvinphos in Wistar rat]. Eisei Shikenjo Hokoku. 1990;(108):45-51. The male and female rats showed dose-related inhibition of serum cholinesterase activity and erythrocyte acetylcholinesterase activity. |
2(0,0,0,2) | Details |
| 17522960 | Berger J, Valdez S, Puschner B, Leutenegger CM, Gardner IA, Madigan JE: Effects of oral tetrachlorvinphos fly control (Equitrol) administration in horses: physiological and behavioural findings. Vet Res Commun. 2008 Jan;32(1):75-92. Epub 2007 May 24. TCVP exerts its effect by inhibiting the enzyme cholinesterase (ChE) leading to the accumulation of the neurotransmitter (AChE) in synapses of the central and peripheral nervous systems. |
1(0,0,0,1) | Details |
| 14680990 | Karanth S, Pope C: In vitro inhibition of blood cholinesterase activities from horse, cow, and rat by tetrachlorvinphos. Int J Toxicol. 2003 Nov-Dec;22(6):429-33. In many species, including horse and man, plasma contains predominantly butyrylcholinesterase whereas red blood cells in all species express exclusively acetylcholinesterase. |
1(0,0,0,1) | Details |