| 14575675 |
Fujita K, Nagaoka M, Komatsu Y, Iwahashi H: Yeast pheromone signaling pathway as a bioassay to assess the effect of chemicals on mammalian peptide hormones. Ecotoxicol Environ Saf. 2003 Nov;56(3):358-66.
The yeast mating pheromone alpha factor is homologous to mammalian gonadoliberins such as luteinizing hormone-releasing hormone (LHRH).
However, in a cells treated with certain chemicals used in pesticides, fungicides, and industrial products (i.e., TPN (CAS No. 1897-45-6), thiuram (CAS No. 137-26-8), captan (CAS No. 133-06-2), oxine-copper (CAS No. 10380-28-6), zineb (CAS No. 12122-67-7), and ziram (CAS No. 137-30-4)) the induction of shmoo formation was suppressed even when commercial alpha-factor was added. |
1(0,0,0,1) |
Details |