Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name oxamyl
CAS

Reference List

PubMed Abstract RScore(About this table)
6326020 Wright DJ, Birtle AJ, Roberts IT: Triphasic locomotor response of a plant-parasitic nematode to avermectin: inhibition by the GABA antagonists bicuculline and picrotoxin. Parasitology. 1984 Apr;88 ( Pt 2):375-82.

In contrast, the acetylcholinesterase inhibitor, oxamyl, causes initial hyperactivity of juveniles followed by a progressive decline in movement.
31(0,1,1,1) Details
19449386 Anguiano GA, Amador A, Moreno-Legorreta M, Arcos-Ortega F, Vazquez-Boucard C: Effects of exposure to oxamyl, carbofuran, dichlorvos, and lindane on acetylcholinesterase activity in the gills of the Pacific oyster Crassostrea gigas. Environ Toxicol. 2009 May 15.
16(0,0,2,6) Details
10871426 Parker ML, Goldstein MI: Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris). Arch Environ Contam Toxicol. 2000 Aug;39(2):233-42.

We quantified B-esterase buffering of organophosphate (diazinon and methyl parathion) and carbamate (aldicarb and oxamyl) toxicity in nestling European starlings (Sturnus vulgaris).
Theoretically, compounds affected by BChE removal would have a higher affinity for BChE or carboxylesterase (CaE) than acetylcholinesterase (AChE).
3(0,0,0,3) Details
19934164 Moser VC, McDaniel KL, Phillips PM, Lowit AB: Time-course, dose-response, and age comparative sensitivity of N-methyl carbamates in rats. Toxicol Sci. 2010 Mar;114(1):113-23. Epub 2009 Nov 24.

N-Methyl carbamate insecticides are reversible inhibitors of central and peripheral acetylcholinesterase (ChE).
To study potential age-related differences, we evaluated seven carbamates (carbaryl, carbofuran, formetanate, methiocarb, methomyl, oxamyl, and propoxur) in preweanling (17 days old or postnatal day [PND] 17) male rats.
1(0,0,0,1) Details
1318238 Fayez V, Kilgore WW: Acute toxic effects of oxamyl in the rat. Fundam Appl Toxicol. 1992 Jan;18(1):155-9.

The compound inhibited brain and blood acetylcholinesterase significantly in the first few hours of exposure.
1(0,0,0,1) Details