Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name oxamyl
CAS

Reference List

PubMed Abstract RScore(About this table)
3699328 Kennedy GL Jr: Acute toxicity studies with oxamyl. . Fundam Appl Toxicol. 1986 Apr;6(3):423-9.

Repeated-dose studies, orally in rats and dermally in rabbits, showed oxamyl to be noncumulative, with the target system being the nervous system mediated through cholinesterase inhibition.
83(1,1,1,3) Details
17197007 Padilla S, Marshall RS, Hunter DL, Lowit A: Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur. Toxicol Appl Pharmacol. 2007 Mar;219(2-3):202-9. Epub 2006 Nov 15.
82(1,1,1,2) Details
3732661 Kennedy GL Jr: Chronic toxicity, reproductive, and teratogenic studies with oxamyl. . Fundam Appl Toxicol. 1986 Jul;7(1):106-18.

Rats fed a diet containing oxamyl at 500 ppm showed clinical signs of cholinesterase inhibition and body weight loss within 2 days.
63(0,2,2,3) Details
17159234 Lassiter TL, Brimijoin S: A method to determine precise benchmark doses for carbamate anticholinesterases. Toxicol Sci. 2007 Mar;96(1):154-61. Epub 2006 Dec 11.

In determining benchmark doses for risk assessment and regulation of carbamate anticholinesterase pesticides like formetanate, oxamyl, and methomyl, one needs to quantitate low levels of cholinesterase inhibition.
34(0,1,1,4) Details
10871426 Parker ML, Goldstein MI: Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris). Arch Environ Contam Toxicol. 2000 Aug;39(2):233-42.

The toxicities of diazinon, methyl parathion, and oxamyl were affected by the removal of butyrylcholinesterase (BChE) using the specific inhibitor tetraisopropylpyrophosphoramide (iso-OMPA).
32(0,1,1,2) Details
17504769 McDaniel KL, Padilla S, Marshall RS, Phillips PM, Podhorniak L, Qian Y, Moser VC: Comparison of acute neurobehavioral and cholinesterase inhibitory effects of N-methylcarbamates in rat. Toxicol Sci. 2007 Aug;98(2):552-60. Epub 2007 May 15.

The chemicals tested were carbaryl, carbofuran, formetanate, methiocarb, methomyl, oxamyl, and propoxur.
3(0,0,0,3) Details
17931764 Grauer E, Levy A: Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats. Toxicology. 2007 Dec 5;242(1-3):1-6. Epub 2007 Sep 5.

One month after exposure to approximately 1LD (50) of the carbamates aldicarb and oxamyl, the hypothermic effect of oxotremorine was similar to that found in saline-treated control group.
2(0,0,0,2) Details
2035247 Iyaniwura TT: Relative inhibition of rat plasma and erythrocyte cholinesterases by pesticide combinations. Vet Hum Toxicol. 1991 Apr;33(2):166-8.

A selected combination of carbamate pesticides (carbofuran, oxamyl and propoxur were examined for cholinesterase (ChE) inhibition.
32(0,1,1,2) Details