Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name 2,4,5-T
CAS 2-(2,4,5-trichlorophenoxy)acetic acid

Reference List

PubMed Abstract RScore(About this table)
15261164 Bukowska B: 2,4,5-T and 2,4,5-TCP induce oxidative damage in human erythrocytes: the role of glutathione. Cell Biol Int. 2004;28(7):557-63.

In this study, damage parameters [levels of reduced glutathione (GSH) and total glutathione; activity of glutathione reductase (GR); activities of catalase (CAT) and superoxide dismutase (SOD); levels of adenine nucleotides and adenine energy charge (AEC)] were measured in human erythrocytes exposed in vitro to 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) and its metabolite 2,4,5-trichlorophenol (2,4,5-TCP).
31(0,1,1,1) Details
2334865 Mikalsen SO, Holen I, Sanner T: Morphological transformation and catalase activity of Syrian hamster embryo cells treated with hepatic peroxisome proliferators, TPA and nickel sulphate. Cell Biol Toxicol. 1990 Jan;6(1):1-13.

The abilities of the hepatic peroxisome proliferators (HPPs) clofibrate, di (2-ethylhexyl) phthalate (DEHP), mono (2-ethylhexyl)-phthalate (MEHP), 2,4-dichlorophenoxy acetic acid (2,4-D), 2,4,5-trichlorophenoxy acetic acid (2,4,5-T) and tiadenol to induce morphological transformation and to increase the catalase activity of Syrian hamster embryo (SHE) cells were studied.
11(0,0,1,6) Details
2225320 Abdellatif AG, Preat V, Vamecq J, Nilsson R, Roberfroid M: Peroxisome proliferation and modulation of rat liver carcinogenesis by 2,4-dichlorophenoxyacetic acid, 2,4,5-trichlorophenoxyacetic acid, perfluorooctanoic acid and nafenopin. Carcinogenesis. 1990 Nov;11(11):1899-902.

In comparison with controls, NAF and PFOA caused a 60-and 24-fold increase inthe peroxisomal beta-oxidation of fatty acids respectively, but only about a 2-fold increase in the catalase activity, 2,4-D and/or 2,4,5-T were much less active in this respect, giving approximately a doubling in the rate of fatty acid oxidation.
31(0,1,1,1) Details
6704149 Kawashima Y, Katoh H, Nakajima S, Kozuka H, Uchiyama M: Effects of 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid on peroxisomal enzymes in rat liver. Biochem Pharmacol. 1984 Jan 15;33(2):241-5.

The effects of feeding 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) on the level of peroxisomal enzymes in rat liver were studied.
The concentration of triglyceride in serum was decreased and the activity of cyanide-insensitive palmitoyl-CoA oxidation, catalase and carnitine acetyltransferase increased.
1(0,0,0,1) Details