Name | CYP2B6 |
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Synonyms | CPB 6; CPB6; CYP2B; CYP2B protein; CYP2B6; CYPIIB 6; CYPIIB6; Cytochrome P450 2B6… |
Name | metolachlor |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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16277416 | Kawahigashi H, Hirose S, Ohkawa H, Ohkawa Y: Phytoremediation of metolachlor by transgenic rice plants expressing human CYP2B6. J Agric Food Chem. 2005 Nov 16;53(23):9155-60. We evaluated the degradation of metolachlor by CYP2B6 rice plants to confirm the metabolic activity of the introduced CYP2B6. |
107(1,1,5,7) | Details |
15853388 | Hirose S, Kawahigashi H, Ozawa K, Shiota N, Inui H, Ohkawa H, Ohkawa Y: Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides. J Agric Food Chem. 2005 May 4;53(9):3461-7. At germination, R (1) seeds of transgenic rice plants expressing CYP2B6 (CYP2B6 rice) showed a high tolerance to 5 microM metolachlor, a preemergence herbicide that is degraded by CYP2B6. |
90(1,1,2,5) | Details |
11133395 | Coleman S, Linderman R, Hodgson E, Rose RL: Comparative metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes. Environ Health Perspect. 2000 Dec;108(12):1151-7. We have also shown that the cytochrome P450 isoforms responsible for human metabolism of acetochlor, butachlor, and metolachlor are CYP3A4 and CYP2B6. |
31(0,1,1,1) | Details |
16608219 | Kawahigashi H, Hirose S, Ohkawa H, Ohkawa Y: Phytoremediation of the herbicides atrazine and metolachlor by transgenic rice plants expressing human CYP1A1, CYP2B6, and CYP2C19. J Agric Food Chem. 2006 Apr 19;54(8):2985-91. |
7(0,0,1,2) | Details |
18685273 | Kawahigashi H, Hirose S, Ohkawa H, Ohkawa Y: Transgenic rice plants expressing human p450 genes involved in xenobiotic metabolism for phytoremediation. J Mol Microbiol Biotechnol. 2008;15(2-3):212-9. Epub 2008 Jul 28. Rice (Oryza sativa) is a good candidate for this purpose and has been transformed with genes encoding cytochrome P450 monooxygenases CYP1A1, CYP2B6, and CYP2C19. Transgenic plants were able to remove atrazine and metolachlor from soil. |
1(0,0,0,1) | Details |