Protein Information

Name acetolactate synthase
Synonyms Acetolactate synthase; OR10B1P

Compound Information

Name metsulfuron
CAS 2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoic acid

Reference List

PubMed Abstract RScore(About this table)
15223257 Cedergreen N, Spliid NH, Streibig JC: Species-specific sensitivity of aquatic macrophytes towards two herbicides. Ecotoxicol Environ Saf. 2004 Jul;58(3):314-23.

To compare the species sensitivity between different groups of herbicides, SSDs were constructed from a published study on the sulfonylurea metsulfuron-methyl, an inhibitor of acetolactate synthase.
81(1,1,1,1) Details
16691366 Riethmuller-Haage I, Bastiaans L, Harbinson J, Kempenaar C, Kropff MJ: Influence of the acetolactate synthase inhibitor metsulfuron-methyl on the operation, regulation and organisation of photosynthesis in Solanum nigrum. Photosynth Res. 2006 Jun;88(3):331-41. Epub 2006 May 12.
62(0,2,2,2) Details
16953494 Kaushik S, Streibig JC, Cedergreen N: Activities of mixtures of soil-applied herbicides with different molecular targets. Pest Manag Sci. 2006 Nov;62(11):1092-7.

Results showed that mixtures of herbicides with similar molecular targets, i.e. chlorsulfuron and metsulfuron (acetolactate synthase (ALS) inhibitors), and with different molecular targets, i.e. pendimethalin (microtubule assembly inhibitor) and pretilachlor (very long chain fatty acids (VLCFAs) inhibitor), followed the ADM.
31(0,1,1,1) Details
17054088 Pasquer F, Ochsner U, Zarn J, Keller B: Common and distinct gene expression patterns induced by the herbicides 2,4-dichlorophenoxyacetic acid, cinidon-ethyl and tribenuron-methyl in wheat. Pest Manag Sci. 2006 Dec;62(12):1155-67.


Sulfonylurea compounds such as tribenuron-methyl specifically inhibit acetolactate synthase and are rapidly detoxified, but the activity of some of the resulting metabolites could explain later changes in gene expression.
1(0,0,0,1) Details
16667530 Milhomme H, Bastide J: Uptake and Phytotoxicity of the Herbicide Metsulfuron Methyl in Corn Root Tissue in the Presence of the Safener 1,8-Naphthalic Anhydride. Plant Physiol. 1990 Jun;93(2):730-738.

0(0,0,0,0) Details