Name | growth arrest specific protein 6 |
---|---|
Synonyms | AXL receptor tyrosine kinase ligand; AXL stimulatory factor; AXLLG; AXSF; GAS 6; GAS6; Growth arrest specific 6; Growth arrest specific protein 6… |
Name | warfarin |
---|---|
CAS |
PubMed | Abstract | RScore(About this table) | |
---|---|---|---|
19564549 | Park JK, Theuer S, Kirsch T, Lindschau C, Klinge U, Heuser A, Plehm R, Todiras M, Carmeliet P, Haller H, Luft FC, Muller DN, Fiebeler A: Growth arrest specific protein 6 participates in DOCA-induced target-organ damage. Hypertension. 2009 Aug;54(2):359-64. Epub 2009 Jun 29. Furthermore, because warfarin interferes with Gas 6 protein expression, the findings could be of clinical relevance for anticoagulant choices. |
93(1,1,1,13) | Details |
18495950 | Danziger J: warfarin, and vascular calcification. . Clin J Am Soc Nephrol. 2008 Sep;3(5):1504-10. Epub 2008 May 21. Warfarin prevents the activation of MGP and Gas-6, and in animals, induces vascular calcification. |
-dependent proteins, 84(1,1,1,4) | Details |
19692494 | McCann JC, Ames BN: linked to diseases of aging?. Am J Clin Nutr. 2009 Oct;90(4):889-907. Epub 2009 Aug 19. Results indicate that 5 VKD proteins that are required for coagulation had critical functions (knockouts were embryonic lethal), whereas the knockouts of 5 less critical VKD proteins [osteocalcin, matrix Gla protein (Mgp), growth arrest specific protein 6, transforming growth factor beta-inducible protein (Tgfbi or betaig-h3), and periostin] survived at least through weaning. Genetic loss of less critical VKD proteins, dietary inadequacy, human polymorphisms or mutations, and vitamin K deficiency induced by chronic anticoagulant (warfarin/ therapy are all linked to age-associated conditions: bone fragility after loss (osteocalcin) and arterial calcification linked to cardiovascular disease (Mgp). |
an example of triage theory: is micronutrient inadequacy 1(0,0,0,1) | Details |