Protein Information

Name FVIII
Synonyms AHF; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII precursor; DXS1253E; F8; F8 protein; F8B…

Compound Information

Name warfarin
CAS

Reference List

PubMed Abstract RScore(About this table)
19794141 Skupsky J, Zhang AH, Su Y, Scott DW: A role for thrombin in the initiation of the immune response to therapeutic factor VIII. Blood. 2009 Nov 19;114(21):4741-8. Epub 2009 Sep 30.

If mice are treated with the anticoagulant warfarin, which depletes other coagulation factors including thrombin, there is a reduced immune response to FVIII.
87(1,1,1,7) Details