Protein Information

Name phosphoenolpyruvate carboxykinase
Synonyms PCK 1; PCK1; PEP carboxykinase; PEPCK cytosolic; PEPCK 1; PEPCK C; PEPCKC…

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
12898129 Mazzetti MB, Taira MC, Lelli SM, Dascal E, Basabe JC, de Viale LC: Hexachlorobenzene impairs glucose metabolism in a rat model of porphyria cutanea tarda: a mechanistic approach. Arch Toxicol. 2004 Jan;78(1):25-33. Epub 2003 Jul 29.

For this purpose, a time-course study on gluconeogenic enzymes, pyruvate carboxylase (PC), phosphoenolpyruvate carboxykinase (PEPCK), glucose-6-phosphatase (G-6-Pase) and on pyruvate kinase (PK), a glycolytic enzyme, was carried out.
1(0,0,0,1) Details
17182006 Lelli SM, Ceballos NR, Mazzetti MB, Aldonatti CA, San Martin de Viale LC: Hexachlorobenzene as hormonal disruptor--studies about glucocorticoids: their hepatic receptors, adrenal synthesis and plasma levels in relation to impaired gluconeogenesis. Biochem Pharmacol. 2007 Mar 15;73(6):873-9. Epub 2006 Nov 18.

In Wistar rats, hexachlorobenzene (HCB) depresses the gluconeogenic enzyme phosphoenolpyruvate-carboxykinase (PEPCK).
6(0,0,1,1) Details