Protein Information

Name ferritin (protein family or complex)
Synonyms Ferritin; Ferritins

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
1959868 Siersema PD, van Helvoirt RP, Ketelaars DA, Cleton MI, de Bruijn WC, Wilson JH, van Eijk HG: Iron and uroporphyrin in hepatocytes of inbred mice in experimental porphyria: a biochemical and morphological study. Hepatology. 1991 Dec;14(6):1179-88.

A single uroporphyrin crystal, surrounded by ferritin iron, was observed in a hepatocyte of a mouse treated with hexachlorobenzene alone.
14(0,0,2,4) Details
8269485 Siersema PD, Cleton-Soeteman MI, de Bruijn WC, ten Kate FJ, van Eijk HG, Wilson JH: Ferritin accumulation and uroporphyrin crystal formation in hepatocytes of C57BL/10 mice: a time-course study. Cell Tissue Res. 1993 Nov;274(2):405-12.

Uroporphyria was induced by the intraperitoneal administration of hexachlorobenzene plus iron dextran and of iron dextran alone.
5(0,0,0,5) Details
2940809 Wainstok de Calmanovici R, Rios de Molina MC, San Martin de Viale LC: The role of iron in the hexachlorobenzene induced porphyria. Acta Physiol Pharmacol Latinoam. 1985;35(4):481-91.

The effect in vitro of ferritin, haemin and inorganic iron at different concentrations on normal PCL activity was also assayed.
1(0,0,0,1) Details
3596748 Wainstok de Calmanovici R, Rios de Molina Mdel C, Vila MC, San Martin de Viale LC: Studies on the role of iron in the alterations observed in hexachlorobenzene-induced porphyria. IARC Sci Publ. 1986;(77):497-503.

Further, the effects of the addition of: both heated and non-heated HCB-porphyric liver preparations, iron as sulfate, ferritin and haemin and alpha alpha'-bipyridyl and 8-hydroxyquinoline were studied on the following enzymes: delta-aminolaevulinic acid synthase, delta-aminolaevulinic acid dehydratase, porphobilinogenase and porphyrinogen carboxy-lyase.
1(0,0,0,1) Details