Protein Information

Name carcinoembryonic antigen
Synonyms CD66e; CEA; CD66e antigen; CEACAM 5; CEACAM5; Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen related cell adhesion molecule 5 precursor…

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
18522717 De Coster S, Koppen G, Bracke M, Schroijen C, Den Hond E, Nelen V, Van de Mieroop E, Bruckers L, Bilau M, Baeyens W, Schoeters G, van Larebeke N: Pollutant effects on genotoxic parameters and tumor-associated protein levels in adults: a cross sectional study. Environ Health. 2008 Jun 3;7:26.

Also, we found significant associations between values of PSA above the p90 and higher values of urinary cadmium, between values of p53 above the p90 and higher serum levels of p,p'-DDE, hexachlorobenzene and marker PCBs (PCB 138, 153 and 180) and between serum levels of p,p'-DDE above the p90 and higher serum values of carcinoembryonic antigen.
9(0,0,1,4) Details
18708379 Ketelslegers HB, Gottschalk RW, Koppen G, Schoeters G, Baeyens WF, van Larebeke NA, van Delft JH, Kleinjans JC: Multiplex genotyping as a biomarker for susceptibility to carcinogenic exposure in the FLEHS biomonitoring study. Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):1902-12.

In both age groups, relationships between endogenous exposure to organochloride substances (polychlorinated biphenyl, hexachlorobenzene, dichlorodiphenyl dichloroethane), metals (cadmium, lead), and urinary metabolites (1-hydroxypyrene, trans-trans muconic acid) versus genotoxic effects (Comet assay and micronuclei in lymphocytes, and urinary 8-hydroxydeoxyguanosine) were investigated.
In addition, in the study among adults, the relationship of these exposures with several tumor markers (prostate-specific antigen, carcinoembryonic antigen, and p53) was tested.
1(0,0,0,1) Details