Protein Information

Name parathyroid hormone
Synonyms PTH; Parathormone; Parathyrin; Parathyroid hormone; Parathyroid hormone precursor; Parathormones; Parathyrins; Parathyroid hormones…

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
2714525 Andrews JE, Courtney KD, Stead AG, Donaldson WE: Hexachlorobenzene-induced hyperparathyroidism and osteosclerosis in rats. Fundam Appl Toxicol. 1989 Feb;12(2):242-51.

Hexachlorobenzene (HCB) exposure has been shown to alter the normal concentrations of parathyroid hormone and 1,25-dihydroxyvitamin D3 in rats and to result in osteoporosis in humans.
8(0,0,1,3) Details
3351979 Andrews JE, Courtney KD, Donaldson WE: Impairment of calcium homeostasis by hexachlorobenzene (HCB) exposure in Fischer 344 rats. J Toxicol Environ Health. 1988;23(3):311-20.

Serum cholesterol, alanine aminotransferase (ALT), 1, 25-dihydroxy-vitamin D3 [1,25-(OH) 2D3], and parathyroid hormone (PTH) were significantly elevated when compared to control values.
1(0,0,0,1) Details