| Name | estrogen receptor |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | hexachlorobenzene |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorobenzene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18992306 | Li J, Li N, Ma M, Giesy JP, Wang Z: In vitro profiling of the endocrine disrupting potency of organochlorine pesticides. Toxicol Lett. 2008 Dec 15;183(1-3):65-71. Epub 2008 Oct 17. The objectives of this study were to determine and compare the ability of p,p'-dichlorodiphenylethane (p,p'-DDE), p,p'-dichlorodiphenyltrichloroethane (p,p'-DDT), hexachlorobenzene (HCB) and r-hexachlorocyclohexane (r-HCH) to interact with ERalpha, androgen receptor (AR), progesterone receptor (PR) and -related receptor (ERRgamma) using a set of recombined yeast strains expressing beta-galactosidase, under control of ERalpha, AR, PR or ERRgamma. |
83(1,1,1,3) | Details |
| 19879930 | Garcia MA, Pena D, Alvarez L, Cocca C, Pontillo C, Bergoc R, de Pisarev DK, Randi A: Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor alpha-dependent manner in MCF-7 breast cancer cell line. Toxicol Lett. 2010 Feb 1;192(2):195-205. Epub 2009 Oct 30. |
10(0,0,1,5) | Details |
| 16859517 | Munoz-de-Toro M, Durando M, Beldomenico PM, Beldomenico HR, Kass L, Garcia SR, Luque EH: Estrogenic microenvironment generated by organochlorine residues in adipose mammary tissue modulates biomarker expression in ERalpha-positive breast carcinomas. Breast Cancer Res. 2006;8(4):R47. The most frequently detected compounds were p,p'-dichlorodiphenyldichloroethylene, hexachlorobenzene and beta-hexachlorocyclohexane. |
5(0,0,0,5) | Details |
| 16705413 | Noguerol TN, Boronat S, Casado M, Raldua D, Barcelo D, Pina B: Evaluating the interactions of vertebrate receptors with persistent pollutants and antifouling pesticides using recombinant yeast assays. Anal Bioanal Chem. 2006 Jul;385(6):1012-9. Epub 2006 May 17. In this work we use two yeast systems to test the ability of different chemicals to bind and activate two vertebrate receptors which are intimately related to adverse biological effects of pollution in exposed fauna: the estrogen receptor (ER) and the aryl hydrocarbon receptor (AhR). The panel of compounds analysed here includes well-known pollutants, like PCBs, pp'-DDT and hexachlorobenzene, together with the less-known, emerging putative pollutants, such as Sea-Nine, Irgarol and diuron. |
1(0,0,0,1) | Details |
| 19182854 | Balaam JL, Chan-Man Y, Roberts PH, Thomas KV: Identification of nonregulated pollutants in North Sea-produced water discharges. Environ Toxicol Chem. 2009 Jun;28(6):1159-67. Produced water samples were characterized for the presence of aryl hydrocarbon receptor (AhR) and estrogen receptor (ER) agonists using the dioxin-responsive, chemical-activated luciferase gene expression assay (DR-CALUX) and yeast screen (YES) bioassays. These include persistent organic contaminants, such as hexachlorobenzene, decachlorobiphenyl, and octachlorodibenzofuran. |
1(0,0,0,1) | Details |
| 15061365 | Charlier C, Foidart JM, Pitance F, Herman P, Gaspard U, Meurisse M, Plomteux G: Environmental dichlorodiphenyltrichlorethane or hexachlorobenzene exposure and breast cancer: is there a risk?. Clin Chem Lab Med. 2004 Feb;42(2):222-7. |
0(0,0,0,0) | Details |