Protein Information

Name integrin linked kinase
Synonyms 59 kDa serine/threonine protein kinase; ILK; ILK protein; ILK 1; ILK 2; ILK1; ILK2; Integrin linked protein kinase 1…

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
16162845 Plante I, Cyr DG, Charbonneau M: Involvement of the integrin-linked kinase pathway in hexachlorobenzene-induced gender-specific rat hepatocarcinogenesis. Toxicol Sci. 2005 Dec;88(2):346-57. Epub 2005 Sep 14.
7(0,0,1,2) Details
16679308 Plante I, Charbonneau M, Cyr DG: Activation of the integrin-linked kinase pathway downregulates hepatic connexin32 via nuclear Akt. Carcinogenesis. 2006 Sep;27(9):1923-9. Epub 2006 May 5.

We have shown that Cx32 is downregulated in the liver of female rats exposed to hexachlorobenzene (HCB), an epigenetic environmental carcinogen.
2(0,0,0,2) Details