Protein Information

Name delta aminolevulinate dehydratase
Synonyms ALAD; ALADH; Aminolevulinate dehydratase; Delta aminolevulinate dehydratase; Delta aminolevulinic acid dehydratase; PBGS; Porphobilinogen synthase; Porphyria acute hepatic…

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
3813879 Kondo M, Shimizu Y: The effects of ethanol, estrogen, and hexachlorobenzene on the activities of hepatic delta-aminolevulinate synthetase, delta-aminolevulinate dehydratase, and uroporphyrinogen decarboxylase in male rats. Arch Toxicol. 1986 Oct;59(3):141-5.
 7(0,0,1,2) Details
104753 Geike F: Effect of hexachlorobenzene (HCB) on the activity of some enzymes from Tetrahymena pyriformis. Bull Environ Contam Toxicol. 1978 Nov;20(5):640-6.

At a dose level of 0.001 ppm the activity of delta-aminolevulinate dehydratase, hexokinase, and pyruvate kinase remained unaffected but was increased for glutamic-oxaloacetic transaminase, glutamic dehydrogenase, isocitrate dehydrogenase, and malate dehydrogenase while 0.1 ppm HCB increased the activity of all enzymes studied, the only exception being glutamic-pyruvic transaminase, the activity of which was depressed by HCB exposure.		 1(0,0,0,1) Details