Protein Information

Name K ras
Synonyms C H RAS; Transforming protein p21; N ras; HRAS1; HRASP; C H ras 1 protein N terminal fragment (37 AA); C has/bas p21 protein; C ras Ki 2 protein…

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
1423854 Rumsby PC, Evans JG, Phillimore HE, Carthew P, Smith AG: Search for Ha-ras codon 61 mutations in liver tumours caused by hexachlorobenzene and Aroclor 1254 in C57BL/10ScSn mice with iron overload. Carcinogenesis. 1992 Oct;13(10):1917-20.
 7(0,0,1,2) Details
15531428 Howsam M, Grimalt JO, Guino E, Navarro M, Marti-Rague J, Peinado MA, Capella G, Moreno V: Organochlorine exposure and colorectal cancer risk. Environ Health Perspect. 2004 Nov;112(15):1460-6.

Alpha-hexachlorocyclohexane, hexachlorobenzene, and p,p'-DDE (4,4'-dichlorodiphenyltrichloroethene) showed nonsignificant increases in risk.
We assessed point mutations in K-ras and p53 genes in tissue samples by polymerase chain reaction/single-strand conformation polymorphism and assessed expression of p53 protein by immunohistochemical methods.		 1(0,0,0,1) Details