Protein Information

Name B28
Synonyms B28; FAPP1 associated protein 1; FASP 1; FASP1; FAPP1 associated protein 1s

Compound Information

Name cresol
CAS methylphenol

Reference List

PubMed Abstract RScore(About this table)
9755897 Richards JP, Stickelmeyer MP, Flora DB, Chance RE, Frank BH, DeFelippis MR: Self-association properties of monomeric insulin analogs under formulation conditions. Pharm Res. 1998 Sep;15(9):1434-41.


The self-association properties of these analogs were compared to those of human insulin and the rapid-acting insulin analog Lys (B28) Pro (B29)-human insulin.
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9034217 Birnbaum DT, Kilcomons MA, DeFelippis MR, Beals JM: Assembly and dissociation of human insulin and LysB28ProB29-insulin hexamers: a comparison study. Pharm Res. 1997 Jan;14(1):25-36.


PURPOSE: Investigations into the kinetic assembly and dissociation of hexameric LysB28ProB29-human insulin (LysPro), a rapid-acting insulin analog produced by the sequence inversion of amino acids at positions B28 and B29, were designed to explain the impact that the sequence inversion has on the formulation and pharmacokinetics of the insulin analog.
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9708987 Whittingham JL, Edwards DJ, Antson AA, Clarkson JM, Dodson GG: Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues. Biochemistry. 1998 Aug 18;37(33):11516-23.

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