| Name | xanthine oxidase |
|---|---|
| Synonyms | XDH; XDHA; XO; XOD; XOR; Xanthene dehydrogenase; Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase… |
| Name | cresol |
|---|---|
| CAS | methylphenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12387302 | Yeung SY, Lan WH, Huang CS, Lin CP, Chan CP, Chang MC, Jeng JH: Scavenging property of three cresol isomers against H2O2, and Food Chem Toxicol. 2002 Oct;40(10):1403-13. This study showed that three cresol isomers, and are H2O2 scavengers with a 50% inhibitory concentration (IC50) of 502, 6.7 and 10.16 microM, respectively. o-, m- and were also shown to be effective scavengers of radicals generated by /xanthine oxidase with an IC50 of 282, 153 and > 4000 microM, respectively, as analyzed by luminometer. o-, m- and showed protective effects on the DNA breaks generated by H2O2/FeCl2 and FeCl3//H2O2 systems at concentrations ranging from 70 microM to 1.43 mM, o-, m- and also showed differential protective effects against DNA breaks induced by 0.17% NaOCl with 100% inhibitory concentration (IC100) of about 10, 1 and 10 mM, respectively. |
31(0,1,1,1) | Details |
| 9366006 | Romer W, Oettel M, Menzenbach B, Droescher P, Schwarz S: Novel estrogens and their radical scavenging effects, iron-chelating, and total antioxidative activities: 17 alpha-substituted analogs of delta 9 (11)-dehydro-17 Steroids. 1997 Nov;62(11):688-94. Whereas the classical 17 as well as selected phenolic compounds was only moderately inhibiting iron-dependent lipid peroxidation and stimulating total antioxidative activity, besides delta 9 (11)-dehydro-17 (J 1213), novel estrogens such as C-17-oriented side chain analogs of 17 (J 843, J 872, and J 897) and delta 9 (11)-dehydro homologs (J 844, J 864, and J 898) directly altered the iron redox chemistry and diminished the formation of radicals generated by a /xanthine oxidase-dependent luminescence reaction to a great extent. |
1(0,0,0,1) | Details |
| 8889496 | Pico I, Myara I, Pech-Amsellem MA, Vedie B, Chappey B, Moatti N: Oxidative modification of low-density lipoprotein by the human hepatoma cell line HepG2. Free Radic Res. 1996 Oct;25(4):321-36. We found that LDL is modified by HepG2 cells through a peroxidative mechanism, as judged by an increase in TBARS content (which was prevented in the presence of the antioxidants 2,6-di-tertbutyl-cresol and probucol), increased degradation by J774 macrophages, decreased internalization by MRC5 fibroblasts, and aggregation of apo B. |
0(0,0,0,0) | Details |