| Name | alpha tubulin |
|---|---|
| Synonyms | Alpha tubulin ubiquitous; Tubulin K alpha 1; Tubulin alpha ubiquitous chain; K alpha 1; K ALPHA 1 protein; alpha tubulin; K alpha 1s; K ALPHA 1 proteins… |
| Name | griseofulvin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 4041962 | Schibler MJ, Cabral FR: Maytansine-resistant mutants of Chinese hamster ovary cells with an alteration in alpha-tubulin. Can J Biochem Cell Biol. 1985 Jun;63(6):503-10. The alpha-tubulin mutants were cross-resistant to other microtubule disrupting drugs such as griseofulvin, vinblastine, and colcemid, but were more sensitive to the microtubule-stabilizing agent taxol than the wild-type parental cells. |
9(0,0,1,4) | Details |
| 3053299 | Schatten G, Simerly C, Asai DJ, Szoke E, Cooke P, Schatten H: Acetylated alpha-tubulin in microtubules during mouse fertilization and early development. Dev Biol. 1988 Nov;130(1):74-86. After treatment with cold, colcemid, or griseofulvin, the remaining stable microtubules are acetylated, but immunoHVEM observations suggest that these fibers might not have been acetylated prior to microtubule disruption. |
3(0,0,0,3) | Details |
| 7458914 | Roobol A, Pogson CI, Gull K: Identification and characterization of microtubule proteins from myxamoebae of Physarum polycephalum. Biochem J. 1980 Aug 1;189(2):305-12. Amoebal tubulin has been identified as having an alpha-subunit, mol.wt. 54 000, which co-migrates with brain alpha-tubulin and a beta-subunit, mol.wt. 50 000, which co-migrates with Tetrahymena ciliary beta-tubulin. The mitotic inhibitor griseofulvin (7-chloro-2',4,6-trimethoxy-6'-methylspiro [benzofuran-2 (3H),1'-cyclohex-2' -ene] -3,4'-dione), which binds to brain microtubule-associated proteins and inhibits brain microtubule assembly in vitro, affected co-polymer microtubule protein in a similar way, but to a slightly greater extent. |
1(0,0,0,1) | Details |
| 2969337 | That TC, Rossier C, Barja F, Turian G, Roos UP: Induction of multiple germ tubes in Neurospora crassa by antitubulin agents. Eur J Cell Biol. 1988 Apr;46(1):68-79. The microtubule (MT) cytoskeleton of N. crassa could be revealed by indirect immunofluorescence with the monoclonal antibody YOL 1/34 directed against yeast alpha-tubulin. This drug induced multipolar germination at 8 microM, and griseofulvin only at 140 microM. |
1(0,0,0,1) | Details |
| 12658461 | Noel C, Gerbod D, Delgado-Viscogliosi P, Fast NM, Younes AB, Chose O, Roseto A, Capron M, Viscogliosi E: Morphogenesis during division and griseofulvin-induced changes of the microtubular cytoskeleton in the parasitic protist, Trichomonas vaginalis. Parasitol Res. 2003 Apr;89(6):487-94. Epub 2003 Jan 21. The behavior of microtubular structures during division was followed by immunofluorescence in Trichomonas vaginalis using an anti-alpha-tubulin monoclonal antibody together with nuclear staining by DAPI, allowing us to describe successive mitotic stages. |
1(0,0,0,1) | Details |