| Name | microtubule associated proteins |
|---|---|
| Synonyms | GOLSYN; Golgi localized syntaphilin related protein; Golgi localized syntaphilin related proten A; Golgi localized syntaphilin related proten B; Golgi localized syntaphilin related proten C; Microtubule associated protein; SYBU; Syntabulin… |
| Name | griseofulvin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7458914 | Roobol A, Pogson CI, Gull K: Identification and characterization of microtubule proteins from myxamoebae of Physarum polycephalum. Biochem J. 1980 Aug 1;189(2):305-12. The mitotic inhibitor griseofulvin (7-chloro-2',4,6-trimethoxy-6'-methylspiro [benzofuran-2 (3H),1'-cyclohex-2' -ene] -3,4'-dione), which binds to brain microtubule-associated proteins and inhibits brain microtubule assembly in vitro, affected co-polymer microtubule protein in a similar way, but to a slightly greater extent. |
82(1,1,1,2) | Details |
| 9439658 | Migliore L, Testa A, Scarpato R, Pavese N, Petrozzi L, Bonuccelli U: Spontaneous and induced aneuploidy in peripheral blood lymphocytes of patients with Alzheimer's disease. Hum Genet. 1997 Dec;101(3):299-305. To evaluate the sensitivity to aneuploidogenic agents, in vitro treatment of lymphocytes of affected individuals was performed by adding griseofulvin, a chemical whose supposed target is microtubule-associated protein (s). |
81(1,1,1,1) | Details |
| 852576 | Roobol A, Gull K, Pogson I: Evidence that griseofulvin binds to a microtubule associated protein. FEBS Lett. 1977 Mar 15;75(1):149-53. |
81(1,1,1,1) | Details |
| 17612874 | Ko EM, Lowry RB, Martin RH: Analysis of sperm karyotypes in a patient treated with griseofulvin. . Arch Androl. 2007 May-Jun;53(3):157-60. Griseofulvin is known to interfere with chromosome segregation by binding to microtubule-associated proteins. |
81(1,1,1,1) | Details |
| 10051481 | Kenner L, Zatloukal K, Stumptner C, Eferl R, Denk H: Altered microtubule-associated tau messenger RNA isoform expression in livers of griseofulvin- and 3,5-diethoxycarbonyl-1, 4-dihydrocollidine-treated mice. Hepatology. 1999 Mar;29(3):793-800. Tau proteins belong to the family of microtubule-associated proteins (MAPs), which so far have been mostly detected in neuronal cells. |
1(0,0,0,1) | Details |
| 6848174 | Gupta RS: Podophyllotoxin-resistant mutants of Chinese hamster ovary cells: cross-resistance studies with various microtubule inhibitors and podophyllotoxin analogues. Cancer Res. 1983 Feb;43(2):505-12. The cross-resistances of several mutants of Chinese hamster ovary cells which have been obtained after one and two selection steps in the presence of the microtubule inhibitor podophyllotoxin (PodRI and PodRII mutants, respectively) towards various other inhibitors of microtubule assembly (e.g., colchicine, Colcemid, vinblastine, griseofulvin, maytansine, steganacin, nocodazole, and taxol) have been examined. Studies on the binding of [3H] podophyllotoxin to cytoplasmic extracts indicate that one of the PodRII mutants which has been shown previously to be affected in a Mr 66,000 to 68,000 microtubule-associated protein shows reduced binding of the drug in comparison to the parental PodS and PodRI cells. |
1(0,0,0,1) | Details |
| 588267 | Roobol A, Gull K, Pogson CI: Griseofulvin-induced aggregation of microtubule protein. Biochem J. 1977 Oct 1;167(1):39-43. This aggregate contains approx. 90% of the microtubule-associated proteins originally present in the microtubule protein. |
1(0,0,0,1) | Details |
| 6493232 | Gupta RS: Griseofulvin resistance mutation of Chinese hamster ovary cells that affects the apparent molecular weight of a congruent to 200,000-dalton protein. Mol Cell Biol. 1984 Sep;4(9):1761-8. It is suggested that protein P5 and its isoelectric variant P6 may constitute microtubule-associated proteins. |
1(0,0,0,1) | Details |