| Name | albumin |
|---|---|
| Synonyms | ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619… |
| Name | griseofulvin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 4054199 | Schafer-Korting M, Korting HC, Mutschler E: Human plasma and skin blister fluid levels of griseofulvin following a single oral dose. Eur J Clin Pharmacol. 1985;29(1):109-13. In plasma 84% of griseofulvin was bound to proteins, predominantly to albumin; binding in SBF and CBF was 72 and 82%, respectively. 3 h after drug administration the free concentration in plasma significantly exceeded the free concentrations in SBF and CBF. |
81(1,1,1,1) | Details |
| 18603402 | Robin MA, Descatoire V, Pessayre D, Berson A: Steatohepatitis-inducing drugs trigger cytokeratin cross-links in hepatocytes. Toxicol In Vitro. 2008 Sep;22(6):1511-9. Epub 2008 Jul 7. The formation of MDB has been previously reproduced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine or griseofulvin administration which cross-link CK8 by tissue transglutaminase, thus forming an entangled network, from which MDB progressively arise. The present study also provides the first evidence that MDA might directly participate in MDB formation, as this reactive agent cross-linked purified CK8 or albumin in vitro, disrupted the cytokeratin network of isolated hepatocytes, and bridged CK8 molecules. |
1(0,0,0,1) | Details |
| 8557388 | Schafer-Korting M, Korting HC, Rittler W, Obermuller W: Influence of serum protein binding on the in vitro activity of anti-fungal agents. Infection. 1995 Sep-Oct;23(5):292-7. The ratios of IC30- and MIC-values with and without serum protein (albumin, alpha- and gamma-globulin, human plasma) were related to the loss of susceptibility expected according to the free-drug hypothesis. IC30- and MIC-ratios for miconazole were 7 and 13 (observed) vs. 12-20 (expected), for fluconazole 1.5 and 3.5 vs. 1.1, for amphotericin B 10 vs. 11-20, for griseofulvin 3.6 vs. 4, and for terbinafine 61 vs. 100. |
1(0,0,0,1) | Details |
| 3711677 | Hawkins CW, Bickers DR, Mukhtar H, Elmets CA: Cutaneous photosensitization: murine ear swelling as a marker of the acute response. J Invest Dermatol. 1986 Jun;86(6):638-42. Tissue injury evoked by HpD and light was accompanied by extravasation of intravenously administered 125I-labeled albumin in the irradiated ears, indicating that photosensitization was accompanied by transudation of serum into the site of tissue injury. An in vivo correlation of this approach was verified by detection of measurable increase in ear thickness in irradiated mice rendered porphyric by the ingestion of a griseofulvin-containing diet. |
1(0,0,0,1) | Details |
| 1141379 | Redman CM, Banerjee D, Howell K, Palade GE: Colchicine inhibition of plasma protein release from rat hepatocytes. . J Cell Biol. 1975 Jul;66(1):42-59. Colchicine, both in vitro and in vivo, inhibits secretion of albumin and other plasma proteins. Vinblastine also inhibits plasma protein secretion but lumicolchicine, griseofulvin, and cytochalasin B do not. |
1(0,0,0,1) | Details |
| 3881283 | Hathcock JN: Metabolic mechanisms of drug-nutrient interactions. . Fed Proc. 1985 Jan;44(1 Pt 1):124-9. High-fat meals enhance the absorption of griseofulvin and some other drugs. High-fat meals increase plasma concentrations of free fatty acids and thereby displace many drugs from binding sites on plasma albumin. |
1(0,0,0,1) | Details |