| Name | cytochrome bc1 |
|---|---|
| Synonyms | Cytochrome bc1; D3S3191; UQCRC 1; UQCRC1; Ubiquinol cytochrome C reductase complex core protein I mitochondrial; Ubiquinol cytochrome c reductase core protein I; Ubiquinol cytochrome C reductase complex core protein I mitochondrials; Ubiquinol cytochrome c reductase core protein Is |
| Name | azoxystrobin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11561403 | Steinfeld U, Sierotzki H, Parisi S, Poirey S, Gisi U: Sensitivity of mitochondrial respiration to different inhibitors in Venturia inaequalis. Pest Manag Sci. 2001 Sep;57(9):787-96. The sensitivity of Venturia inaequalis field isolates to inhibitors of the cytochrome bc1 complex at the Qo site (QoIs) was characterised at the molecular, biochemical and physiological level, and compared to other respiration inhibitors. Cross-resistance was observed among QoIs such as trifloxystrobin, azoxystrobin, famoxadone, strobilurin B and myxothiazol. |
2(0,0,0,2) | Details |
| 12233180 | Ziogas BN, Markoglou AN, Tzima A: A non-Mendelian inheritance of resistance to strobilurin fungicides in Ustilago maydis. Pest Manag Sci. 2002 Sep;58(9):908-16. Mutants of Ustilago maydis (DC) Corda with high resistance to azoxystrobin (RF 164 to 4714, based on EC50 values), an inhibitor of mitochondrial electron transport at the cytochrome bc1 complex, were isolated in a mutation frequency of 2.3 x 10 (-7) after nitrosoguanidine mutagenesis and selection on media containing 1 microgram ml-1 azoxystrobin in addition to 0.5 mM salicylhydroxamate (SHAM), a specific inhibitor of -resistant (alternative) respiration. |
162(2,2,2,2) | Details |
| 16368254 | Zheng YJ: Molecular basis for the enantioselective binding of a novel class of cytochrome bc1 complex inhibitors. J Mol Graph Model. 2006 Sep;25(1):71-6. Epub 2005 Dec 20. Furthermore, the mode of binding of azoxystrobin has also been clarified. |
2(0,0,0,2) | Details |
| 12525495 | Xiao K, Engstrom G, Rajagukguk S, Yu CA, Yu L, Durham B, Millett F: Effect of famoxadone on photoinduced electron transfer between the iron- center and cytochrome c1 in the cytochrome bc1 complex. J Biol Chem. 2003 Mar 28;278(13):11419-26. Epub 2003 Jan 13. |
1(0,0,0,1) | Details |
| 19928849 | Zhao PL, Wang L, Zhu XL, Huang X, Zhan CG, Wu JW, Yang GF: Subnanomolar inhibitor of cytochrome bc1 complex designed by optimizing interaction with conformationally flexible residues. J Am Chem Soc. 2010 Jan 13;132(1):185-94. Eight new compounds were designed and synthesized, among which compound 5c, with a K (i) value of 570 pM, was identified as the most promising drug or fungicide candidate, significantly more potent than the commercially available bc (1) inhibitors, including azoxystrobin (AZ), kresoxim-methyl (KM), and pyraclostrobin (PY). |
1(0,0,0,1) | Details |