| Name | cytochrome b |
|---|---|
| Synonyms | COB; CYTB; Cytochrome b; Cytochrome b of complex III; MT CYB; MTCYB; mitochondrially encoded cytochrome b; Cytochrome bs… |
| Name | azoxystrobin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18943515 | Amil AF, Heaney SP, Stanger C, Shaw MW: Dynamics of QoI Sensitivity in Mycosphaerella fijiensis in Costa Rica During 2000 to 2003. Phytopathology. 2007 Nov;97(11):1451-7. ABSTRACT From 1997 onward, the strobilurin fungicide azoxystrobin was widely used in the main banana-production zone in Costa Rica against Mycosphaerella fijiensis var. difformis causing black Sigatoka of banana. The cause was a single point mutation from to in the fungal target protein, cytochrome b gene. |
1(0,0,0,1) | Details |
| 17143847 | Toffolatti SL, Serrati L, Sierotzki H, Gisi U, Vercesi A: Assessment of QoI resistance in Plasmopara viticola oospores. Pest Manag Sci. 2007 Feb;63(2):194-201. QoI fungicides, inhibitors of mitochondrial respiration at the Qo site of cytochrome b in the mitochondrial bc (1) enzyme complex, are commonly applied in vineyards against Plasmopara viticola (Berk. & MA Curtis) Berl. & De Toni. In order to evaluate the resistance risk and its development, two different methods, biological and molecular, were applied to measure the sensitivity of oospores differentiated in vineyards, both treated and untreated with azoxystrobin, from 2000 to 2004. |
1(0,0,0,1) | Details |
| 15739234 | Paplomatas EJ, Pappas AC, Syranidou E: Molecular characterization and biological response to respiration inhibitors of Pyricularia isolates from ctenanthe and rice plants. Pest Manag Sci. 2005 Jul;61(7):691-8. The molecular profile and the biological response of isolates of Pyricularia oryzae Cavara obtained from ctenanthe to two strobilurins (azoxystrobin, kresoxim-methyl) and the phenylpyridinamine fungicide fluazinam were characterized, and compared with isolates from rice plants. |
0(0,0,0,0) | Details |
| 11561403 | Steinfeld U, Sierotzki H, Parisi S, Poirey S, Gisi U: Sensitivity of mitochondrial respiration to different inhibitors in Venturia inaequalis. Pest Manag Sci. 2001 Sep;57(9):787-96. Cross-resistance was observed among QoIs such as trifloxystrobin, azoxystrobin, famoxadone, strobilurin B and myxothiazol. |
0(0,0,0,0) | Details |
| 15912560 | Fisher N, Meunier B: Re-examination of inhibitor resistance conferred by Qo-site mutations in cytochrome b using yeast as a model system. Pest Manag Sci. 2005 Oct;61(10):973-8. QoI resistance mutations from fungal plant pathogens (G143A and F129L), malaria agent Plasmodium sp (Y279C/S), and Pneumocystis carinii (L275F), an opportunistic pathogenic fungus of man, were introduced into yeast cytochrome b and their effect on the binding of a variety of natural (myxothiazol and stigmatellin) and synthetic (atovaquone, azoxystrobin and pyraclostrobin) inhibitors to the bc1 complex monitored. |
35(0,1,1,5) | Details |
| 19662660 | Wei CZ, Katoh H, Nishimura K, Ishii H: Site-directed mutagenesis of the cytochrome b gene and development of diagnostic methods for identifying QoI resistance of rice blast fungus. Pest Manag Sci. 2009 Dec;65(12):1344-51. BACKGROUND: It is possible that a single nucleotide polymorphism (SNP) (G143A mutation) in the cytochrome b gene could confer resistance to outside inhibiting (QoI) fungicides (strobilurins) in rice blast fungus because this mutation caused a high level of resistance to fungicides such as azoxystrobin in Pyricularia grisea Sacc. and other fungal plant pathogens. |
34(0,1,1,4) | Details |
| 19444805 | Ishii H, Fountaine J, Chung WH, Kansako M, Nishimura K, Takahashi K, Oshima M: Characterisation of QoI-resistant field isolates of Botrytis cinerea from citrus and strawberry. Pest Manag Sci. 2009 Aug;65(8):916-22. RESULTS: QoI-resistant isolates of B. cinerea grew well on PDA plates containing kresoxim-methyl or azoxystrobin at 1 mg L (-1), supplemented with 1 mM of n-propyl an inhibitor of alternative oxidase, whereas the growth of sensitive isolates was strongly suppressed. In resistant isolates, the mutation at amino acid position 143 of the cytochrome b gene, known to be the cause of high QoI resistance in various fungal pathogens, was found, but only occasionally. |
3(0,0,0,3) | Details |
| 18943331 | Ishii H, Fraaije BA, Sugiyama T, Noguchi K, Nishimura K, Takeda T, Amano T, Hollomon DW: Occurrence and molecular characterization of strobilurin resistance in cucumber powdery mildew and downy mildew. Phytopathology. 2001 Dec;91(12):1166-71. ABSTRACT Between 1998 and 1999, control failure of powdery mildew (Podosphaera fusca) and downy mildew (Pseudoperonospora cubensis) by the strobilurin fungicides azoxystrobin and kresoxim-methyl was observed in cucumber-growing areas of Japan. Fragments of the fungicide-targeted mitochondrial cytochrome b gene were polymerase chain reaction amplified from total pathogen DNA and their sequences analyzed to elucidate the molecular mechanism of resistance. |
3(0,0,0,3) | Details |
| 12612806 | Avila-Adame C, Koller W: Characterization of spontaneous mutants of Magnaporthe grisea expressing stable resistance to the Qo-inhibiting fungicide azoxystrobin. Curr Genet. 2003 Mar;42(6):332-8. Epub 2003 Jan 30. The class of Qo-inhibiting fungicides (QoIs) act as respiration inhibitors by binding to the Qo center of cytochrome b. |
3(0,0,0,3) | Details |
| 15312779 | Esser L, Quinn B, Li YF, Zhang M, Elberry M, Yu L, Yu CA, Xia D: Crystallographic studies of oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc (1) complex. J Mol Biol. 2004 Jul 30;341(1):281-302. Crystal structures of bovine bc (1) in complex with the specific Q (o) site inhibitors azoxystrobin, MOAS, myxothiazol, stigmatellin and 5-undecyl-6-hydroxy-4,7-dioxobenzothiazole were determined. Residues and secondary structure elements that are capable of discriminating different classes of Q (o) site inhibitors were identified for the cytochrome b subunit. |
2(0,0,0,2) | Details |
| 12639047 | Avila-Adame C, Koller W: Impact of alternative respiration and target-site mutations on responses of germinating conidia of Magnaporthe grisea to Qo-inhibiting fungicides. Pest Manag Sci. 2003 Mar;59(3):303-9. Qo-inhibiting fungicides act as respiration inhibitors by binding to the Qo center of cytochrome b. In the absence of a host, alternative respiration provided a > 500-fold rescue from azoxystrobin during the germination of conidia derived from four wild-type isolates of M. grisea. |
2(0,0,0,2) | Details |
| 18943171 | Kim YS, Dixon EW, Vincelli P, Farman ML: Field Resistance to Strobilurin (Q (o) I) Fungicides in Pyricularia grisea Caused by Mutations in the Mitochondrial Cytochrome b Gene. Phytopathology. 2003 Jul;93(7):891-900. The Pyricularia grisea isolates possessing the G143A substitution were significantly more resistant to azoxystrobin and trifloxystrobin, in vitro, than those having F129L. |
2(0,0,0,2) | Details |
| 18943516 | Ishii H, Yano K, Date H, Furuta A, Sagehashi Y, Yamaguchi T, Sugiyama T, Nishimura K, Hasama W: Molecular Characterization and Diagnosis of QoI Resistance in Cucumber and Eggplant Fungal Pathogens. Phytopathology. 2007 Nov;97(11):1458-66. In both pathogens, a mutation at position 143 from to (G143A) was detected in the cytochrome b gene that encodes for the fungicide-targeted protein. The protective efficacy of the full dose of azoxystrobin decreased when the populations of powdery and downy mildews contained resistant isolates at 10%. |
2(0,0,0,2) | Details |
| 19418479 | Furuya S, Suzuki S, Kobayashi H, Saito S, Takayanagi T: Rapid method for detecting resistance to a QoI fungicide in Plasmopara viticola populations. Pest Manag Sci. 2009 Aug;65(8):840-3. RESULTS: The authors have developed a rapid method for detecting resistance to a QoI fungicide, azoxystrobin, in P. viticola populations using the nested PCR-RFLP method. With this method, a -to- substitution was discovered at codon 143 in the cytochrome b gene of P. viticola populations found in Japan. |
1(0,0,0,1) | Details |
| 19307035 | Zhang Z, Zhu Z, Ma Z, Li H: A molecular mechanism of azoxystrobin resistance in Penicillium digitatum UV mutants and a PCR-based assay for detection of azoxystrobin-resistant strains in packing- or store-house isolates. Int J Food Microbiol. 2009 May 31;131(2-3):157-61. Epub 2009 Feb 25. Analysis of the cytochrome b gene structure of P. digitatum (Pdcyt b) showed the absence of type I intron in the first hot spot region of mutation. |
1(0,0,0,1) | Details |