| Name | phosphodiesterase |
|---|---|
| Synonyms | CAMP specific phosphodiesterase variant PDE4A 10; CAMP specific phosphodiesterase variant TM3; CAMP specific phosphodiesterase; Cyclic AMP phosphodiesterase PDE4A11; Cyclic AMP specific phosphodiesterase HSPDE4A10; DPDE 2; DPDE2; PDE 4… |
| Name | anthraquinone |
|---|---|
| CAS | 9,10-anthracenedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2155616 | Matsuda Y, Nakanishi S, Nagasawa K, Kase H: Inhibition by new anthraquinone compounds, K-259-2 and KS-619-1, of calmodulin-dependent cyclic nucleotide phosphodiesterase. Biochem Pharmacol. 1990 Mar 1;39(5):841-9. K-259-2 and KS-619-1, novel anionic anthraquinone metabolites isolated from culture broth of microorganisms, inhibited activation of bovine brain phosphodiesterase induced by calmodulin (CaM), or limited proteolysis with almost equal potency. |
83(1,1,1,3) | Details |
| 8950490 | Yamana K, Mitsui T, Yoshioka J, Isuno T, Nakano H: Incorporation of two anthraquinonylmethyl groups into the 2'-O-positions of oligonucleotides: increased affinity and sequence specificity of anthraquinone-modified oligonucleotides in hybrid formation with DNA and RNA. Bioconjug Chem. 1996 Nov-Dec;7(6):715-20. The base compositions and the presence of anthraquinone group (s) in the oligonucleotides were verified with enzymatic digestion (snake venom phosphodiesterase and alkaline phosphatase) analysis and UV-vis spectral measurements. |
6(0,0,1,1) | Details |
| 8247737 | Ono A, Dan A, Matsuda A: Synthesis of oligonucleotides carrying linker groups at 1'-position of sugar residues. Nucleic Acids Symp Ser. 1993;(29):13-4. A novel 2'- analogue carrying an aminobutyl linker at 1'-position of the sugar residue was synthesized and incorporated into oligonucleotides, then an anthraquinone derivative was attached to the amino group. The oligonucleotides carrying the linker groups were more resistant to nuclease P1 and venom phosphodiesterase than an unmodified oligonucleotide. |
1(0,0,0,1) | Details |
| 8305519 | Ono A, Dan A, Matsuda A: Nucleosides and nucleotides. 121. Bioconjug Chem. 1993 Nov-Dec;4(6):499-508. Novel 2'- analogues carrying aminoalkyl linkers at the 1'-position of the sugar residues were synthesized and incorporated into oligonucleotides, then intercalating groups such as an anthraquinone derivative and a pyrene derivative were attached to the amino groups. The oligonucleotides carrying the linker groups were more resistant to nuclease P1 and venom phosphodiesterase than an unmodified oligonucleotide. |
1(0,0,0,1) | Details |