Name | xanthine oxidase |
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Synonyms | XDH; XDHA; XO; XOD; XOR; Xanthene dehydrogenase; Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase… |
Name | anthraquinone |
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CAS | 9,10-anthracenedione |
PubMed | Abstract | RScore(About this table) | |
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7639535 | Malisza KL, Hasinoff BB: Production of by iron (III)-anthraquinone complexes through self-reduction and through reductive activation by the xanthine oxidase/ system. Arch Biochem Biophys. 1995 Aug 1;321(1):51-60. |
82(1,1,1,2) | Details |
12688675 | Pawlowska J, Tarasiuk J, Wolf CR, Paine MJ, Borowski E: Differential ability of cytostatics from anthraquinone group to generate free radicals in three enzymatic systems: NADH dehydrogenase, NADPH cytochrome P450 reductase, and xanthine oxidase. Oncol Res. 2003;13(5):245-52. |
7(0,0,1,2) | Details |
2166575 | Alegria AE, Rodriguez MS, Hernandez J: Semiquinones derived from anthraquinone-containing antitumor drugs can partition into bilayers. Biochim Biophys Acta. 1990 Jul 20;1035(1):51-5. Semiquinones derived from anthraquinone-containing antitumor drugs (doxorubicin, daunorubicin and 4'-epidoxorubicin) were generated by the /xanthine oxidase system in argon-saturated buffer (pH 7.4) in the presence of egg-yolk multilamellar vesicles (MLVs) containing 1 mol% of a doxylstearic acid (DSA) isomer. |
6(0,0,1,1) | Details |
223343 | Lengfelder E, Elstner EF: superoxide dismutase in Euglena gracilis. Z Naturforsch C. 1979 May-Jun;34C(5-6):374-80. Both proteins show -insensitive superoxide dismutase activity in the "classical" superoxide dismutase assay, using -xanthine oxidase as O2.- generator. If O2.- is generated chemically (autoxidation of reduced anthraquinone), photochemically (illuminated or pulse radiolytically, only protein P1 but not P2 shows SOD activity. |
insensitive iron 2(0,0,0,2) | Details |
2753390 | Monteiro HP, Vile GF, Winterbourn CC: Release of iron from ferritin by semiquinone, anthracycline, bipyridyl, and nitroaromatic radicals. Free Radic Biol Med. 1989;6(6):587-91. Compounds were reduced to their corresponding radicals with xanthine oxidase/ under N2 and the release of Fe2+ was monitored by complexation with ferrozine. Ferritin iron was released by a number of bipyridyl radicals including those derived from diquat and paraquat, the anthracycline radicals of adriamycin, daunorubicin and epirubicin, the semiquinones of anthraquinone-2-sulphonate, 1,5 and 2,6-dihydroxyanthraquinone, 1-hydroxyanthraquinone, purpurin, and plumbagin, and the nitroaromatic radicals of nitrofurantoin and metronidazole. |
1(0,0,0,1) | Details |
11197344 | Matsuda H, Morikawa T, Toguchida I, Park JY, Harima S, Yoshikawa M: Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides. Bioorg Med Chem. 2001 Jan;9(1):41-50. In addition, several stilbenes with both the 3- and 4'-methoxyl groups inhibited xanthine oxidase. |
1(0,0,0,1) | Details |
2827582 | Vile GF, Winterbourn CC, Sutton HC: Radical-driven Fenton reactions: studies with paraquat, adriamycin, and anthraquinone 6-sulfonate and ATP, ADP, and iron chelates. Arch Biochem Biophys. 1987 Dec;259(2):616-26. Radicals were generated either radiolytically or enzymatically with xanthine oxidase or ferredoxin reductase. |
1(0,0,0,1) | Details |
2891826 | Mian M, Brunelleschi S, Tarli S, Rubino A, Benetti D, Fantozzi R, Zilletti L: Rhein: an anthraquinone that modulates production from human neutrophils. J Pharm Pharmacol. 1987 Oct;39(10):845-7. |
0(0,0,0,0) | Details |
8646615 | Winston GW, Moore MN, Kirchin MA, Soverchia C: Production of reactive species by hemocytes from the marine mussel, Mytilus edulis: lysosomal localization and effect of xenobiotics. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996 Feb;113(2):221-9. Uptake of the anthraquinone, purpurin, and FeEDTA with DHR greatly amplified fluorescence within the lysosomes. |
0(0,0,0,0) | Details |