Protein Information

Name glucose 6 phosphate isomerase
Synonyms AMF; NLK; PGI; GNPI; GPI; Autocrine motility factor; GPI protein; Glucose 6 phosphate isomerase…

Compound Information

Name metalaxyl
CAS

Reference List

PubMed Abstract RScore(About this table)
18943330 Jaime-Garcia R, Orum TV, Felix-Gastelum R, Trinidad-Correa R, Vanetten HD, Nelson MR: Spatial Analysis of Phytophthora infestans Genotypes and Late Blight Severity on Tomato and Potato in the Del Fuerte Valley Using Geostatistics and Geographic Information Systems. Phytopathology. 2001 Dec;91(12):1156-65.

Isolates of P. infestans were characterized by mating type, allozyme analysis at the glucose-6-phosphate isomerase and peptidase loci, restriction fragment length polymorphism with probe RG57, metalaxyl sensitivity, and aggressiveness to tomato and potato.
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18943951 Derie ML, Inglis DA: Persistence of Complex Virulences in Populations of Phytophthora infestans in Western Washington. Phytopathology. 2001 Jun;91(6):606-12.

ABSTRACT Isolates of Phytophthora infestans, collected from bittersweet, hairy nightshade, petunia, potato, potato vine, and tomato in western Washington, 1998 to 1999, were evaluated for virulence complexity as well as mating type, metalaxyl insensitivity, allozymes of glucose-6-phosphate isomerase and peptidase, and DNA fingerprint with the RG57 probe.
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18945085 Miller JS, Hamm PB, Johnson DA: Characterization of the Phytophthora infestans Population in the Columbia Basin of Oregon and Washington from 1992 to 1995. Phytopathology. 1997 Jun;87(6):656-60.

ABSTRACT Isolates of Phytophthora infestans collected from 1992 to 1995 from potato fields in the Columbia Basin of Oregon and Washington were analyzed for compatibility type, metalaxyl sensitivity, and glucose-6-phosphate isomerase (Gpi) genotype.
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18944419 Jaime-Garcia R, Trinidad-Correa R, Felix-Gastelum R, Orum TV, Wasmann CC, Nelson MR: Temporal and Spatial Patterns of Genetic Structure of Phytophthora infestans from Tomato and Potato in the Del Fuerte Valley. Phytopathology. 2000 Nov;90(11):1188-95.

The isolates were characterized by mating type, allozymes at the glucose-6-phosphate isomerase and peptidase loci, restriction fragment length polymorphism (RFLP) fingerprint with probe RG57, metalaxyl sensitivity, and aggressiveness to tomato and potato.
6(0,0,1,1) Details
15756821 Heremans B, Haesaert G: Diversity of the Phytophthora infestans population in Flanders, Belgium. Commun Agric Appl Biol Sci. 2004;69(4):421-5.

Characteristics of the isolates included in vitro growth rate, mating type, in vitro sensitivity to the phenylamide fungicide metalaxyl-M and allozyme genotype at glucose-6-phosphate isomerase (Gpi) and peptidase (Pep) loci.
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18945115 Forbes GA, Escobar XC, Ayala CC, Revelo J, Ordonez ME, Fry BA, Doucett K, Fry WE: Population Genetic Structure of Phytophthora infestans in Ecuador. Phytopathology. 1997 Apr;87(4):375-80.

Both samples were dominated (> 95%) by a clonal lineage (EC-1) defined from neutral markers: 90/100 genotype for glucose-6-phosphate isomerase, 96/100 genotype for peptidase, A1 mating type, and a previously unreported nuclear DNA fingerprint.
Isolates in the 1993 sample were analyzed for virulence and metalaxyl sensitivity.
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18944234 Grunwald NJ, Flier WG, Sturbaum AK, Garay-Serrano E, van den Bosch TB, Smart CD, Matuszak JM, Lozoya-Saldana H, Turkensteen LJ, Fry WE: Population Structure of Phytophthora infestans in the Toluca Valley Region of Central Mexico. Phytopathology. 2001 Sep;91(9):882-90.

Based on the Glucose-6-phosphate isomerase and Peptidase allozymes, the subpopulations from the three habitats were significantly differentiated in both sampling periods.
In contrast to allozyme data for 1997-98, no differences were found among the three subpopulations for sensitivity to metalaxyl.
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18944872 Goodwin SB, Smart CD, Sandrock RW, Deahl KL, Punja ZK, Fry WE: Genetic Change Within Populations of Phytophthora infestans in the United States and Canada During 1994 to 1996: Role of Migration and Recombination. Phytopathology. 1998 Sep;88(9):939-49.

The high sensitivity of the US-1 genotype to the fungicide metalaxyl also could have reduced opportunities for contact between the mating types in fields where this compound was applied.
Isolates of P. capsici and P. erythroseptica, two other species often found on tomato and potato, could be easily distinguished from each other and from P. infestans using a simple allozyme assay for the enzyme glucose-6-phosphate isomerase.
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12233187 Deahl KL, Cooke LR, Black LL, Wang TC, Perez FM, Moravec BC, Quinn M, Jones RW: Population changes in Phytophthora infestans in Taiwan associated with the appearance of resistance to metalaxyl. Pest Manag Sci. 2002 Sep;58(9):951-8.

This new genotype was an A1 mating type and has the dilocus allozyme genotype 100/100/111, 100/100 for the loci coding for glucose-6-phosphate isomerase and peptidase, respectively.
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