| Name | TRPM 2 |
|---|---|
| Synonyms | AAG 4; TRPM2; AAG4; APOJ; Apo J; Apolipoprotein J; CLI; CLU… |
| Name | vinclozolin |
|---|---|
| CAS | 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11376863 | Nellemann C, Vinggaard AM, Dalgaard M, Hossaini A, Larsen JJ: Quantification of antiandrogen effect determined by Lightcycler technology. Toxicology. 2001 May 28;163(1):29-38. In this study, investigation of expression of prostate specific binding protein polypeptide C3 (PBP C3) and -repressed prostatic message 2 (TRPM-2) in the ventral prostate was performed in 60-days-old castrated Wistar rats treated daily with with or without addition of flutamide or vinclozolin for 7 days in total. |
31(0,1,1,1) | Details |
| 12563111 | Nellemann C, Dalgaard M, Lam HR, Vinggaard AM: The combined effects of vinclozolin and procymidone do not deviate from expected additivity in vitro and in vivo. Toxicol Sci. 2003 Feb;71(2):251-62. Expression of the androgen-responsive gene, TRPM-2, was increased starting at 100 mg/kg vinclozolin. |
7(0,0,1,2) | Details |
| 9007049 | Kelce WR, Lambright CR, Gray LE Jr, Roberts KP: Vinclozolin and p,p'-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism. Toxicol Appl Pharmacol. 1997 Jan;142(1):192-200. Densitometry scans of Northern blots indicated that vinclozolin, p,p'-DDE, and flutamide each induced TRPM-2 mRNA and repressed C3 mRNA compared to vehicle-treated T-implanted controls. |
7(0,0,1,2) | Details |