Protein Information

Name A10
Synonyms A10; IGKV6D 21; IGKV6D21; immunoglobulin kappa variable 6D 21; immunoglobulin kappa variable 6D 21s

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
9260877 Cleary I, Doherty G, Moran E, Clynes M: The multidrug-resistant human lung tumour cell line, DLKP-A10, expresses novel drug accumulation and sequestration systems. Biochem Pharmacol. 1997 May 15;53(10):1493-502.

Metabolic inhibition by antimycin A (but not sodium azide or 2-deoxy-D-glucose) resulted in complete restoration of drug accumulation suggesting the presence of an alternative energy dependent transport mechanism.
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7949184 Slapak CA, Mizunuma N, Kufe DW: Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells. Blood. 1994 Nov 1;84(9):3113-21.

Treatment with sodium azide/2-deoxyglucose, 2,4-dinitrophenol, or monensin, but not verapamil, abolished the vesicular accumulation.
Drug-resistant sublines of the human U-937 myeloid leukemia cell line were selected in doxorubicin concentrations of 10, 40, and 200 ng/mL (designated U-A10, U-A40, and U-A200, respectively).
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