| Name | alpha tubulin |
|---|---|
| Synonyms | Alpha tubulin ubiquitous; Tubulin K alpha 1; Tubulin alpha ubiquitous chain; K alpha 1; K ALPHA 1 protein; alpha tubulin; K alpha 1s; K ALPHA 1 proteins… |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15486199 | Loganzo F, Hari M, Annable T, Tan X, Morilla DB, Musto S, Zask A, Kaplan J, Minnick AA Jr, May MK, Ayral-Kaloustian S, Poruchynsky MS, Fojo T, Greenberger LM: Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin. Mol Cancer Ther. 2004 Oct;3(10):1319-27. However, 4.0 nmol/L HTI-286-selected cells had a point mutation in alpha-tubulin that substitutes Ser for (12) near the nonexchangeable GTP-binding site of alpha-tubulin. Sodium azide treatment partially reversed low HTI-286 accumulation, suggesting involvement of an ATP-dependent drug pump. |
2(0,0,0,2) | Details |
| 9223249 | Lessman CA, Wang T, Gard DL, Woods CW: Microinjection of anti-alpha-tubulin antibody (DM1A) inhibits -induced meiotic maturation and deranges the microtubule array in follicle-enclosed oocytes of the frog, Rana pipiens. Zygote. 1997 Feb;5(1):83-95. By contrast, low doses of microinjected DM1A (46 nl; 2.5 mg/ml), anti-actin (clone KJ43A), anti-cytokeratin (C-11), anti-intermediate filament antibody (IFA), generic IgG (46 nl; 20 mg/ml) or sodium azide (46 nl; 1 mg/ml), an antibody preservative, were without inhibitory effect in this bioassay. |
2(0,0,0,2) | Details |
| 14688152 | Demir AY, Groothuis PG, Nap AW, Punyadeera C, de Goeij AF, Evers JL, Dunselman GA: Menstrual effluent induces epithelial-mesenchymal transitions in mesothelial cells. Hum Reprod. 2004 Jan;19(1):21-9. Sodium azide, an inhibitor of ATP production, and a general kinase inhibitor, antagonized these effects. During the changes the distribution of cytokeratins, fibrillar actin and alpha-tubulin changed. |
1(0,0,0,1) | Details |